Journal ArticleDOI
Immunoglobulin G4-Related Disease
Su Jin Moon,Jun-Ki Min +1 more
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TLDR
Rituximab is reported to be an effective therapy for treatment of IgG4-RD, even without concomitant glucocorticoid therapy, which is the first-line therapy for patients with multiple organ dysfunction and clinical symptoms.Citations
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Immunoglobulin G4-related disease in the stomach presenting as a gastric subepithelial tumor: Case report.
Min Ji Cho,Hee Seok Moon,Hyeon Seok Lee,Jae Ho Park,Ju Seok Kim,Sun Hyung Kang,Eaum Seok Lee,Seok Hyun Kim,Jae Kyu Sung,Byung Seok Lee,Hyun Yong Jeong +10 more
TL;DR: Using alternative preoperative diagnostic methods such as endoscopic ultrasound-guided fine-needle biopsy or the biopsy unroofing technique could spare the patient from unnecessary surgical treatment.
References
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Journal ArticleDOI
IgG4-related hypertrophic pachymeningitis: clinical features, diagnostic criteria, and treatment.
TL;DR: Clinicians should become familiar with this alternative differential diagnosis for IgG4-RHP because a prompt, specific therapeutic approach may avoid long-term neurological complications.
Journal ArticleDOI
Pseudotumors due to IgG4 immune-complex tubulointerstitial nephritis associated with autoimmune pancreatocentric disease.
Lynn D. Cornell,Sonia L. Chicano,Vikram Deshpande,A. Bernard Collins,Martin K. Selig,Gregory Y. Lauwers,Laura Barisoni,Robert B. Colvin +7 more
TL;DR: This type of TIN, typically characterized by a masslike lesion consisting of a lymphoplasmacytic infiltrate with eosinophils and prominent IgG 4-positive plasma cells and immune-complex deposits in the TBM, may be part of a systemic IgG4-related disease, which is described as “IgG5-associated immune complex Multiorgan Autoimmune Disease” (IMAD).
Journal ArticleDOI
Ophthalmic manifestations of IgG4-related disease: single-center experience and literature review.
TL;DR: Ophthalmic involvement is a common manifestation of IgG4-RD and can affect nearly every orbital structure and Rituximab holds promise as an effective steroid-sparing agent or therapy for steroid-resistant cases.
Journal ArticleDOI
Immunology of IgG4‐related disease
TL;DR: The most recent insights on the immunology of IgG4‐RD are reviewed, focusing on the relative contribution of innate and adaptive immune responses to the full pathological phenotype of this fibrotic condition.
Journal ArticleDOI
Prevalence of IgG4-Related Disease in Japan Based on Nationwide Survey in 2009.
TL;DR: The number of patients with autoimmune pancreatitis who visited hospitals in Japan in 2007 was approximately 2709 (95% confidence interval; range 2540–3040); because IgG4-related disease is a new clinical entity, there are no data with regard to its prevalence.