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Open AccessJournal ArticleDOI

Immunoinformatics Approach to Design Multi-Epitope- Subunit Vaccine against Bovine Ephemeral Fever Disease

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TLDR
In this paper, a highly efficacious multi-epitope vaccine candidate was designed against the geographically distributed bovine ephemeral fever virus (BEFV) population.
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This article is published in Vaccine.The article was published on 2021-08-19 and is currently open access. It has received 9 citations till now. The article focuses on the topics: Population.

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Preparation and characterization of nanocurcumin based hybrid virosomes as a drug delivery vehicle with enhanced anticancerous activity and reduced toxicity.

TL;DR: In this article, a formulation of nanocurcumin based hybrid virosomes (NC-virosome) was presented to deliver drugs at targeted sites, which showed 82.6% drug encapsulation efficiency.
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Designing multi-epitope-based vaccine targeting surface immunogenic protein of Streptococcus agalactiae using immunoinformatics to control mastitis in dairy cattle

TL;DR: In this article , a multi-epitope vaccine was designed to be antigenic, immunogenic, non-toxic, and non-allergic, and had a binding affinity with TLR2 and TLR4 based on structural modeling, docking, and molecular dynamics simulation studies.
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Screening of potential antigens from whole proteome and development of multi-epitope vaccine against Rhizopus delemar using immunoinformatics approaches

TL;DR: This is the first multi-epitope vaccine designed against R. delemar through systematic pipelined reverse vaccinology and immunoinformatic approaches and will significantly help in reducing the cost of experimentation as well as improving the efficacy of vaccine therapy against mucormycosis and other pathogenic diseases.
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Mapping Potential Vaccine Candidates Predicted by VaxiJen for Different Viral Pathogens between 2017–2021—A Scoping Review

Zakia Salod, +1 more
- 24 Oct 2022 - 
TL;DR: It is recommended that vaccinologists use the findings of this review as a guide to performing experimental validation for various viruses, with SARS-CoV-2 as a priority, because better vaccines are needed, especially to stay ahead of the emergence of new variants.
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Immunoinformatics Analysis of Citrullinated Antigen as Potential Multi-peptide Lung Cancer Vaccine Candidates for Indonesian Population

TL;DR: In this article , a multi-epitope peptide-based vaccine for non-small-cell lung cancer (NSCLC) utilizing citrullinated peptides was developed.
References
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Journal ArticleDOI

UCSF Chimera--a visualization system for exploratory research and analysis.

TL;DR: Two unusual extensions are presented: Multiscale, which adds the ability to visualize large‐scale molecular assemblies such as viral coats, and Collaboratory, which allows researchers to share a Chimera session interactively despite being at separate locales.
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Comparison of simple potential functions for simulating liquid water

TL;DR: In this article, the authors compared the Bernal Fowler (BF), SPC, ST2, TIPS2, TIP3P, and TIP4P potential functions for liquid water in the NPT ensemble at 25°C and 1 atm.
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Clustal W and Clustal X version 2.0

TL;DR: The Clustal W and ClUSTal X multiple sequence alignment programs have been completely rewritten in C++ to facilitate the further development of the alignment algorithms in the future and has allowed proper porting of the programs to the latest versions of Linux, Macintosh and Windows operating systems.
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Molecular dynamics with coupling to an external bath.

TL;DR: In this paper, a method is described to realize coupling to an external bath with constant temperature or pressure with adjustable time constants for the coupling, which can be easily extendable to other variables and to gradients, and can be applied also to polyatomic molecules involving internal constraints.
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Particle mesh Ewald: An N⋅log(N) method for Ewald sums in large systems

TL;DR: An N⋅log(N) method for evaluating electrostatic energies and forces of large periodic systems is presented based on interpolation of the reciprocal space Ewald sums and evaluation of the resulting convolutions using fast Fourier transforms.
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