Immunomodulatory effects of curcumin.
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Cites background from "Immunomodulatory effects of curcumi..."
...Yadav and his group also reported that curcumin can suppress the PHA-induced proliferation of human peripheral blood mononuclear cells (PBMCs) and inhibit IL-2 expression and NF-κB (51)....
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...Inhibits PHA-stimulated IL-2 production in human PMBCs (51)....
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...In another study, curcumin has been reported to reduce LPS-induced NO production in mouse macrophages (51)....
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...In one of the investigations, curcumin has been found to augment NK-cell cytotoxicity (51)....
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...Inhibits LPS-induced NO production in mouse macrophages (51)....
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421 citations
Cites background from "Immunomodulatory effects of curcumi..."
...Curcumin is an effective scavenger of ROS such as hydroxyl radicals and superoxide anions (Yadav et al., 2005), and it can affect both endoplasmic reticulum (ER) stress and mitochondria functional pathways....
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References
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"Immunomodulatory effects of curcumi..." refers background in this paper
...Curcumin is a potent scavenger of reactive oxygen species like superoxide anions and hydroxyl radicals.([39]) Curcumin treatment resulted in upregulation of NO in NK cells and reactive osygen species in AK-5 tumor cells....
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987 citations
"Immunomodulatory effects of curcumi..." refers background in this paper
...The cyclin D1 is required for the activity of CDK4, which phosphorylates Rb protein, thus releasing E2F to mediate the G1 to S transition, in turn leading to DNA synthesis and cell cycle progression.([35]) There is not enough information about the effect of curcumin on NK cell cytotoxicity....
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674 citations