Impact of Anemia on In-Hospital, One-Month and One-Year Mortality in Patients with Acute Coronary Syndrome from the Middle East
TL;DR: Admission anemia in patients with ACS from six Middle-Eastern countries was strongly associated with mortality at in-hospital, one-month, and at one-year, Hence, admission anemia must be considered in the initial risk assessment of ACS patients along with other risk scores.
Abstract: Aim The aim of this study was to evaluate the impact of admission anemia on in-hospital, one-month, and one-year mortality in patients from the Middle East with acute coronary syndrome (ACS).
Cites background or methods from "Impact of Anemia on In-Hospital, On..."
...This table reports data from two meta-analyses [9,14] and six observational studies [15-20] that were not included in these meta-analyses....
...Table 1 summarizes the results of two meta-analyses [9,14] and six observational studies [15-20] on the relationship in cardiac adults between anemia and adverse outcomes; a statistically significant association is reported in almost each instance....
Cites result from "Impact of Anemia on In-Hospital, On..."
...They were less often treated with PCI, but more frequently with CABG, which might be an indicator of more advanced coronary artery disease....
...In line, previous studies demonstrated that anemic patients were less often treated with PCI [18, 21] and experienced worse outcomes after PCI, e....
...Due to the lower risk of bleeding, the radial access might also be preferable when performing PCI in patients with anemia....
...Three different models were calculated: 1) an unadjusted model, 2) a model adjusted for age and sex, and 3) a model adjusted for age, sex, previous MI, angina pectoris, hyperlipidemia, diabetes, stroke, eGFR, heart rate, AMI type, LVEF, discharge medications, PCI and in-hospital complications....
...In-hospital procedures such as percutaneous coronary intervention (PCI) and coronary artery bypass graft (CABG) were determined by chart review....
"Impact of Anemia on In-Hospital, On..." refers background in this paper
...In addition, the need for blood transfusion due to anemia in the setting of ACS is associated with higher short-term mortality.(10) Furthermore, a low baseline hemoglobin level in ACS patients has been found to be an independent predictor of the risk of in-hospital major bleeding and risk of death and myocardial infarction at 30 days....