Journal ArticleDOI
Impact of anesthetic agents on cerebrovascular physiology in children.
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TLDR
The understanding of the effects of anesthetic agents on the physiology of cerebral vasculature in the pediatric population has significantly increased in the past decade allowing a more rationale decision making in anesthesia management.Abstract:
care to children with neurologic pathologies. The cerebral physiology is influenced by the developmental stage of the child. The understanding of the effects of anesthetic agents on the physiology of cerebral vasculature in the pediatric population has significantly increased in the past decade allowing a more rationale decision making in anesthesia management. Although no single anesthetic technique can be recommended, sound knowledge of the principles of cerebral physiology and anesthetic neuropharmacology will facilitate the care of pediatric neurosurgical patients.read more
Citations
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Volatiles or TIVA: Which is the standard of care for pediatric airway procedures? A pro-con discussion.
Gillian R. Lauder,Mark G. Thomas,Britta S. von Ungern-Sternberg,Britta S. von Ungern-Sternberg,Britta S. von Ungern-Sternberg,Thomas Engelhardt +5 more
TL;DR: This pro‐con discussion examines both volatiles and TIVA, from the perspective of effectiveness, safety, cost, and environmental impact, in an endeavor to justify which technique is the best specifically for pediatric airway procedures.
Journal ArticleDOI
Effects of hemodilution after traumatic brain injury in juvenile rats.
Gianluca Bertolizio,Bruno Bissonnette,Linda J. Mason,Stephen Ashwal,Richard E. Hartman,Suzzanne Marcantonio,Andre Obenaus +6 more
TL;DR: This study investigated the effects of normovolemic hemodilution (21% hematocrit) in a juvenile TBI (jTBI) model and found it safe and effective in both the acute and chronic phases of TBI.
Journal ArticleDOI
Effects of Sedation Performed by an Anesthesiologist on Pediatric Endoscopy: a Single-Center Retrospective Study in Korea
Sung Min Yang,Dae Yong Yi,Geun Joo Choi,In Seok Lim,Soo Ahn Chae,Sin Weon Yun,Na Mi Lee,Su Yeong Kim,Eung Sang Choi +8 more
TL;DR: When sedation is performed by an anesthesiologist, various drugs are used with sufficient doses and complications are reduced, but the discharge time does not change, whereas for performing pediatric endoscopy in Korea, anesthesiologists should be considered for inducing anesthesia.
Journal ArticleDOI
Elevated Cerebral Blood Volume Contributes to Increased FLAIR Signal in the Cerebral Sulci of Propofol-Sedated Children
Julie H. Harreld,Noah D. Sabin,Michael G. Rossi,R Awwad,Wilburn E. Reddick,Ying Yuan,John O. Glass,Qing Ji,Amar Gajjar,Zoltan Patay +9 more
TL;DR: Elevated cortical CBV appears to contribute to increased signal intensity in sulci on noncontrast FLAIR in propofol-sedated children, and the effects of prop ofol on age-related cerebral perfusion and vascular permeability may play a role.
Journal ArticleDOI
Defining hypotension in anesthetized infants by individual awake blood pressure values: a prospective observational study
TL;DR: Blood pressure is the most commonly applied clinical surrogate parameter for tissue perfusion and cerebral autoregulation and Hypotension during anesthesia may contribute to unfavorable outcome in young children.
References
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Journal ArticleDOI
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Journal ArticleDOI
Inhibition of Adrenal Steroidogenesis by the Anesthetic Etomidate
TL;DR: Physicians should be aware that etomidate inhibits adrenal steroidogenesis, and they should consider treating selected patients with corticosteroids if etamidate is used.
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Formation and absorption of cerebrospinal fluid in man.
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Effects of sevoflurane, propofol, and adjunct nitrous oxide on regional cerebral blood flow, oxygen consumption, and blood volume in humans
Kaike K. Kaisti,Jaakko Långsjö,Sargo Aalto,Vesa Oikonen,Hannu Sipilä,Mika Teräs,Susanna Hinkka,Liisa Metsähonkala,Harry Scheinin +8 more
TL;DR: The effects of sevoflurane and propofol as sole anesthetics and in combination with N2O on regional cerebral blood flow, metabolic rate of oxygen (rCMRO2), and blood volume (rCBV) in the living human brain using positron emission tomography are quantified.