Impact of intermittent fasting on health and disease processes
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TLDR
The term periodic fasting (PF) is used to describe eating patterns in which individuals go extended time periods (e.g., 16-48h) with little or no energy intake, with intervening periods of normal food intake, on a recurring basis as mentioned in this paper.About:
This article is published in Ageing Research Reviews.The article was published on 2017-10-01 and is currently open access. It has received 655 citations till now. The article focuses on the topics: Intermittent fasting & Weight loss.read more
Citations
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Journal ArticleDOI
Early Time-Restricted Feeding Improves Insulin Sensitivity, Blood Pressure, and Oxidative Stress Even without Weight Loss in Men with Prediabetes.
Elizabeth F. Sutton,Robbie A. Beyl,Kate S. Early,William T. Cefalu,William T. Cefalu,Eric Ravussin,Courtney M. Peterson,Courtney M. Peterson +7 more
TL;DR: It is demonstrated for the first time in humans that eTRF improves some aspects of cardiometabolic health and that IF's effects are not solely due to weight loss.
Journal ArticleDOI
Facing up to the global challenges of ageing.
TL;DR: Interventions, including changes to lifestyle and medical innovations, are needed to prevent disease and increase late-life health in humans.
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Flipping the Metabolic Switch: Understanding and Applying the Health Benefits of Fasting
Stephen D. Anton,Keelin Moehl,William T. Donahoo,Krisztina Marosi,Stephanie A. Lee,Arch G. Mainous,Christiaan Leeuwenburgh,Mark P. Mattson +7 more
TL;DR: This review is focused on the physiological responses of major organ systems, including the musculoskeletal system, to the onset of the metabolic switch: the point of negative energy balance at which liver glycogen stores are depleted and fatty acids are mobilized (typically beyond 12 hours after cessation of food intake).
Journal ArticleDOI
Intermittent metabolic switching, neuroplasticity and brain health
TL;DR: How intermittent metabolic switching, repeating cycles of a metabolic challenge that induces ketosis (fasting and/or exercise) followed by a recovery period (eating, resting and sleeping), may optimize brain function and resilience throughout the lifespan is considered, with a focus on the neuronal circuits involved in cognition and mood.
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Early Time-Restricted Feeding Improves 24-Hour Glucose Levels and Affects Markers of the Circadian Clock, Aging, and Autophagy in Humans
Humaira Jamshed,Robbie A. Beyl,Deborah L. Della Manna,Eddy S. Yang,Eric Ravussin,Courtney M. Peterson +5 more
TL;DR: Early time-restricted feeding (eTRF) as mentioned in this paper is a form of intermittent fasting that involves having a longer daily fasting period and has been shown to improve cardiometabolic health in rodents and humans.
References
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Body-mass index and incidence of cancer: a systematic review and meta-analysis of prospective observational studies
Andrew G Renehan,Margaret Tyson,Matthias Egger,Matthias Egger,Richard F Heller,Marcel Zwahlen +5 more
TL;DR: Assessment of the strength of associations between BMI and different sites of cancer and differences in these associations between sex and ethnic groups should inform the exploration of biological mechanisms that link obesity with cancer.
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Physiology and Neurobiology of Stress and Adaptation: Central Role of the Brain
TL;DR: As an adjunct to pharmaceutical therapy, social and behavioral interventions such as regular physical activity and social support reduce the chronic stress burden and benefit brain and body health and resilience.
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Long-term weight loss maintenance
Rena R. Wing,Suzanne Phelan +1 more
TL;DR: Weight loss maintenance may get easier over time; after individuals have successfully maintained their weight loss for 2-5 y, the chance of longer-term success greatly increases.
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Comparison of Weight-Loss Diets with Different Compositions of Fat, Protein, and Carbohydrates
Frank M. Sacks,George A. Bray,Vincent J. Carey,Steven R. Smith,Donna H. Ryan,Stephen D. Anton,Katherine McManus,Catherine M. Champagne,Louise M. Bishop,Nancy Laranjo,Meryl S. LeBoff,Jennifer Rood,Lilian de Jonge,Frank L. Greenway,Catherine M. Loria,Eva Obarzanek,Donald A. Williamson +16 more
TL;DR: Low-calorie diets result in clinically meaningful weight loss regardless of which macronutrients they emphasize, and improved lipid-related risk factors and fasting insulin levels.
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Time-Restricted Feeding without Reducing Caloric Intake Prevents Metabolic Diseases in Mice Fed a High-Fat Diet
Megumi Hatori,Christopher Vollmers,Amir Zarrinpar,Amir Zarrinpar,Luciano DiTacchio,Eric A. Bushong,Shubhroz Gill,Mathias Leblanc,Amandine Chaix,Matthew S. Joens,James A. J. Fitzpatrick,Mark H. Ellisman,Satchidananda Panda +12 more
TL;DR: Mice under tRF consume equivalent calories from HFD as those with ad lib access yet are protected against obesity, hyperinsulinemia, hepatic steatosis, and inflammation and have improved motor coordination.
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A Periodic Diet that Mimics Fasting Promotes Multi-System Regeneration, Enhanced Cognitive Performance, and Healthspan
Sebastian Brandhorst,In Young Choi,Min Wei,Chia-Wei Cheng,Sargis Sedrakyan,Gerardo Navarrete,Louis Dubeau,Li Peng Yap,Ryan Park,Manlio Vinciguerra,Stefano Di Biase,Hamed Mirzaei,Mario G. Mirisola,Patra Childress,Lingyun Ji,Susan Groshen,Fabio Penna,Patrizio Odetti,Laura Perin,Peter S. Conti,Yuji Ikeno,Brian K. Kennedy,Pinchas Cohen,Todd E. Morgan,Tanya B. Dorff,Valter D. Longo +25 more