Impulsivity resulting from frontostriatal dysfunction in drug abuse: implications for the control of behavior by reward-related stimuli.
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...…with hypothalamic and brain-stem regions included in autonomic and consummatory responses, while the cortico- striatal-thalamic circuitry is comprised of regions implicated in motor learning, reinforcer evaluation (nucleus accumbens) or stimulus-reward associations (Jentsch and Taylor 1999)....
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...Note that the central nucleus of the amygdala is connected with hypothalamic and brain-stem regions included in autonomic and consummatory responses, while the corticostriatal-thalamic circuitry is comprised of regions implicated in motor learning, reinforcer evaluation (nucleus accumbens) or stimulus-reward associations (Jentsch and Taylor 1999)....
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2,496 citations
Cites background from "Impulsivity resulting from frontost..."
...The prefrontal cortex is less involved in establishing whether a stimulus is positive or negative (valence); rather, it regulates the overall motivational salience and determines the intensity of behavioral responding (13, 14)....
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2,415 citations
Cites background from "Impulsivity resulting from frontost..."
...For a review of the role of the mesolimbic and mesocortical dopamine system in inhibitory control and motivational processes in the rodent and primate brain and their putative impact on drug seeking, see Jentsch and Taylor (63)....
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