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Journal ArticleDOI

In vitro anti-inflammatory activity of vaccinium leschenaultii wight. (vacciniaceae) - an endemic medicinal plant species in nilgiris, the western ghats, india

30 Dec 2016-Vol. 3, Iss: 2, pp 45-47
TL;DR: V. leschenaultia could be used as a potential source of antiinflammatory agent after being found to inhibit paw edema induced by carrageenan in rats.
Abstract: Berries of Vaccinium species have been a source of food and pharmaceutical ingredients. The ethanol, methanol and chloroform extracts of Vaccinium leschenaultia was investigated for anti-inflammatory activity. All the extracts (150 and 300mg/kg each) were found to significantly (P<0.05) inhibit paw edema induced by carrageenan in rats. The results indicated that the methanol extract with the dose of 300mgkg-1 b.w. and the chloroform extract with the dose of 300mgkg-1 b.wt. showed maximum anti-inflammatory activity as compared to the reference drug, Indomethacin. V. leschenaultia could be used as a potential source of antiinflammatory agent.

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References
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Journal ArticleDOI
TL;DR: The chloroform extract of almost all the drugs exhibited interesting activities with ID(50) values ranging between 108 and 498 micro g/cm(2), comparable to that of indomethacin (93 micro g / cm(2)).

238 citations


"In vitro anti-inflammatory activity..." refers background in this paper

  • ...Although it is a defense mechanism, the complex events and mediators that are involved in the inflammatory reaction can induce, maintain or aggravate many diseases (Sosa et al., 2002)....

    [...]

Journal ArticleDOI
TL;DR: The study concluded that the plant substances such as total phenols, flavonoids along with appreciable antioxidant potential could be the supportive evidence to prove both the anti-inflammatory and antiulcer activities of V. leschenaultii.

21 citations

Book ChapterDOI
01 Jan 2007

21 citations


"In vitro anti-inflammatory activity..." refers background in this paper

  • ...The inflammatory response is a physiological characteristic feature of vascularized tissues (Rang et al, 2007)The inflammatory response is a common feature in many diseases and its control is of relevance in the treatment of these pathologies....

    [...]