Inactivation mechanisms of non-thermal plasma on microbes: A review
TL;DR: An overview of the inactivation mechanisms of NTP technology on microbes is provided and the intrinsic and extrinsic factors affecting microbial inactivation effect and the probable mechanisms for microbial in activation are discussed.
About: This article is published in Food Control.The article was published on 2017-05-01. It has received 309 citations till now.
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TL;DR: In this article, the authors present an overview of recent studies on the application of cold plasma in the food industry, including microbial decontamination of food products, packaging material processing, functionality modification of food materials and dissipation of agrochemical residues.
Abstract: Background Cold plasma (CP) is an emerging technology, which has attracted the attention of scientists globally. It was originally developed for ameliorating the printing and adhesion properties of polymers plus a variety of usage domains in electronics. In the last decade, its applications were extended into the food industry as a powerful tool for non-thermal processing, with diverse forms for utilization. Scope and approach This review presents an overview of recent studies on the application of cold plasma in the food industry. Specific areas discussed include microbial decontamination of food products, packaging material processing, functionality modification of food materials and dissipation of agrochemical residues. The application of CP has also been expanded into areas, such as hydrogenation of edible oils, mitigation of food allergy, inactivation of anti-nutritional factors, tailoring of seed germination performance and effluent management. In addition, the paper provides a summary of plasma chemistry and sources, factors influencing plasma efficiency and strategies for augmentation. Furthermore, key areas for future research are highlighted and salient drawbacks are discussed. Key findings and conclusions The recent studies conducted on the interaction of reactive species with food contact surfaces establish plasma processing as an eco-friendly technique with minimal changes to food products, making it a befitting alternative to traditional techniques. Active researches focused on up-scaling for commercial applications are urgently required.
309 citations
TL;DR: In this article, the effects of non-thermal plasma on the quality of dairy products, considering a physicochemical, sensory, and microbiology perspective, are discussed, and a review of the fundamentals, parameters, and technology on cold plasma is presented.
Abstract: Background Thermal pasteurization and sterilization are predominantly used in the dairy industry due to their efficacy in improving the product safety and shelf life. However, heat treatment can cause undesirable protein denaturation, non-enzymatic browning, loss of vitamins and volatile flavor compounds, freezing point depression, and flavour changes. Cold plasma is a non-thermal technology that has gained attention in recent years as a potential alternative method for chemical and thermal disinfection in foods using ambient or moderate temperatures and short treatment times. Scope and approach This review aims to describe the fundamentals, parameters, and technology on cold plasma, discussing the critical processing factors involved in this technology. Also, it describes the mechanisms of microbial inactivation and provides an overview of the effects of non-thermal plasma on the quality of dairy products, considering a physicochemical, sensory and microbiology perspective. Key findings and conclusions Cold plasma uses less aggressive mechanisms of action to the milk matrix when compared to the techniques currently used, and has shown an excellent performance on the elimination of pathogenic and spoilage microorganisms besides maintaining, in many cases, the nutritional, functional, and sensory characteristics of the product.
169 citations
TL;DR: The aim of this topical review is to summarize the state of the art in plasma medicine and connect it to redox biology.
Abstract: Plasma medicine comprises the application of physical plasma directly on or in the human body for therapeutic purposes. Three most important basic plasma effects are relevant for medical applications: i) inactivation of a broad spectrum of microorganisms, including multidrug-resistant pathogens, ii) stimulation of cell proliferation and angiogenesis with lower plasma treatment intensity, and iii) inactivation of cells by initialization of cell death with higher plasma treatment intensity, above all in cancer cells. Based on own published results as well as on monitoring of relevant literature the aim of this topical review is to summarize the state of the art in plasma medicine and connect it to redox biology. One of the most important results of basic research in plasma medicine is the insight that biological plasma effects are mainly mediated via reactive oxygen and nitrogen species influencing cellular redox-regulated processes. Plasma medicine can be considered a field of applied redox biology.
166 citations
TL;DR: This review introduces recent advances and future perspectives in plasma technology, especially in applications related to disinfection and sterilization, and introduces the latest studies, mainly focusing on the potential applications of plasma technology for the inactivation of microorganisms and the degradation of toxins.
Abstract: Recent studies have shown that plasma can efficiently inactivate microbial pathogens such as bacteria, fungi, and viruses in addition to degrading toxins. Moreover, this technology is effective at inactivating pathogens on the surface of medical and dental devices, as well as agricultural products. The current practical applications of plasma technology range from sterilizing therapeutic medical devices to improving crop yields, as well as the area of food preservation. This review introduces recent advances and future perspectives in plasma technology, especially in applications related to disinfection and sterilization. We also introduce the latest studies, mainly focusing on the potential applications of plasma technology for the inactivation of microorganisms and the degradation of toxins.
143 citations
Cites background from "Inactivation mechanisms of non-ther..."
...The inactivation mechanisms of action of plasma remain to be determined [5,6,31,77]....
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TL;DR: It was demonstrated that 30 s cold plasma treatment resulted in more than 4 log CFU/mL reduction under 50 W, while the quality attributes of apple juice were not significantly affected, therefore, cold plasma technology is a promising alternative substitute of traditional thermal processing for juice pasteurization.
Abstract: Atmospheric cold plasma (ACP) is a promising non‐thermal technology in food industry. In this study, a dielectric barrier discharge (DBD)‐ACP exhibited strong bactericidal effect on Escherichia coliin apple juice. Under a 30 to 50 W input power, less than 40 s treatment time was required for DBD‐ACP to result in 3.98 to 4.34 log CFU/mL reduction of E. coliin apple juice. The inactivation behavior of ACP on E. coliwas well described by the Weibull model. During the treatment, the cell membrane of E. coliwas damaged severely by active species produced by plasma, such as hydrogen peroxide, ozone and nitrate. In addition, the ACP exposure had slight effect on the °Brix, pH, titratable acidity (TA), color values, total phenolic content, and antioxidant capacity of apple juice. However, higher level of DBD‐ACP treatment, 50 W for more than 10 s in this case, resulted in significant change of the pH, TA, color and total phenolic content of apple juice. The results in this study have provided insight in potential use of DBD‐ACP as an alternative to thermal processing for fruit juices in food industry. Escherichia coliO157:H7 in apple juice is a potential risk for public health. This study demonstrated that 30 s cold plasma treatment resulted in more than 4 log CFU/mL reduction under 50 W, while the quality attributes of apple juice were not significantly affected. Therefore, cold plasma technology is a promising alternative substitute of traditional thermal processing for juice pasteurization.
129 citations
References
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Book•
28 Oct 1994
TL;DR: In this paper, the authors introduce the concept of particle and energy balance in discharges and introduce the theory of collision dynamics and wave-heated discharges, as well as chemical reactions and equilibrium.
Abstract: 1. Introduction. 2. Basic Plasma Equations and Equilibrium. 3. Atomic Collisions. 4. Plasma Dynamics. 5. Diffusion and Transport. 6. DC Sheaths. 7. Chemical Reactions and Equilibrium. 8. Molecular Collisions. 9. Chemical Kinetics and Surface Processes. 10. Particle and Energy Balance in Discharges. 11. Capacitive Discharges. 12. Inductive Discharges. 13. Wave-Heated Discharges. 14. DC Discharges. 15. Etching. 16. Deposition and Implantation. 17. Dusty Plasmas. 18. Kinetic Theory of Discharges. Appendix A: Collision Dynamics. Appendix B: The Collision Integral. Appendix C: Diffusion Solutions for Variable Mobility Model.
5,728 citations
TL;DR: The physiological origin of MDA is described, its toxicity is highlighted, and the most common methods of detection are insufficiently sensitive and disturbed by interference coming from related species or overestimation derived from stressing analysis conditions.
Abstract: Summary Aim Of the many biological targets of oxidative stress, lipids are the most involved class of biomolecules. Lipid oxidation gives rise to a number of secondary products. Malondialdehyde (MDA) is the principal and most studied product of polyunsaturated fatty acid peroxidation. This aldehyde is a highly toxic molecule and should be considered as more than just a marker of lipid peroxidation. Its interaction with DNA and proteins has often been referred to as potentially mutagenic and atherogenic. This review is intended to briefly describe the physiological origin of MDA, to highlight its toxicity, describe and comment on the most recent methods of detection and discuss its occurrence and significance in pathology. Data synthesis In vivo origin as well as reactivity and consequent toxicity of MDA are reviewed. The most recent and improved procedures for the evaluation of MDA in biological fluids are described and discussed. The evidence of the occurrence of increased MDA levels in pathology is described. Conclusions In the assessment of MDA, the most common methods of detection are insufficiently sensitive and disturbed by interference coming from related species or overestimation derived from stressing analysis conditions. Moreover, no recent nutritional or medical trials report the use of one of the new and more reliable methods, some of which are undoubtedly accessible to virtually all the laboratories provided with a common HPLC or a spectrofluorimeter.
2,077 citations
TL;DR: Foodborne outbreaks associated with fresh produce in the United States have increased in absolute numbers and as a proportion of all reported foodborne outbreaks, and Cyclospora and Escherichia coli O157:H7 were newly recognized as causes of foodborne illness.
1,061 citations
TL;DR: In this paper, the four most important and widely used varieties of non-thermal discharges: corona, dielectric barrier, gliding arc and spark discharge are discussed.
Abstract: There has been considerable interest in non-thermal atmospheric pressure discharges over the past decade due to the increased number of industrial applications. Diverse applications demand a solid physical and chemical understanding of the operational principals of such discharges. This paper focuses on the four most important and widely used varieties of non-thermal discharges: corona, dielectric barrier, gliding arc and spark discharge. The physics of these discharges is closely related to the breakdown phenomena. The main players in electrical breakdown of gases: avalanches and streamers are also discussed in this paper. Although non-thermal atmospheric pressure discharges have been intensively studied for the past century, a clear physical picture of these discharges is yet to be obtained.
885 citations
TL;DR: In this paper, emission spectroscopy and gas detection are used to evaluate important plasma inactivation factors such as UV radiation and reactive species, and it is shown that for non-equilibrium, atmospheric pressure air plasmas, it is the oxygen-based and nitrogen-based reactive species that play the most important role in the inactivation process.
759 citations