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Open AccessJournal ArticleDOI

Increased cancer burden among pesticide applicators and others due to pesticide exposure.

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TLDR
The epidemiological, molecular biology, and toxicological evidence emerging from recent literature assessing the link between specific pesticides and several cancers including prostate cancer, non‐Hodgkin lymphoma, leukemia, multiple myeloma, and breast cancer are integrated.
Abstract
A growing number of well-designed epidemiological and molecular studies provide substantial evidence that the pesticides used in agricultural, commercial, and home and garden applications are associated with excess cancer risk. This risk is associated both with those applying the pesticide and, under some conditions, those who are simply bystanders to the application. In this article, the epidemiological, molecular biology, and toxicological evidence emerging from recent literature assessing the link between specific pesticides and several cancers including prostate cancer, non-Hodgkin lymphoma, leukemia, multiple myeloma, and breast cancer are integrated. Although the review is not exhaustive in its scope or depth, the literature does strongly suggest that the public health problem is real. If we are to avoid the introduction of harmful chemicals into the environment in the future, the integrated efforts of molecular biology, pesticide toxicology, and epidemiology are needed to help identify the human carcinogens and thereby improve our understanding of human carcinogenicity and reduce cancer risk. CA Cancer J Clin 2013;63:120–142. V C 2013 American Cancer Society.*

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Journal ArticleDOI

Trends in Global Agricultural Land Use: Implications for Environmental Health and Food Security

TL;DR: Both the successes and failures of the global food system are reviewed, addressing ongoing debates on pathways to environmental health and food security and calling on plant biologists to lead this effort and help steer humanity toward a safe operating space for agriculture.
Journal ArticleDOI

Soil biodiversity and human health.

TL;DR: Current research indicates that soil biodiversity can be maintained and partially restored if managed sustainably, and promotes the ecological complexity and robustness of soil biodiversity through improved management practices.
Journal ArticleDOI

Non-Hodgkin Lymphoma and Occupational Exposure to Agricultural Pesticide Chemical Groups and Active Ingredients: A Systematic Review and Meta-Analysis

TL;DR: Despite compelling evidence that NHL is associated with certain chemicals, this review indicates the need for investigations of a larger variety of pesticides in more geographic areas, especially in low- and middle-income countries, which were missing in the literature that were reviewed.
Book ChapterDOI

The Hidden and External Costs of Pesticide Use

TL;DR: In this paper, the authors provide a comprehensive review of these costs and their evaluation and define four categories of costs: regulatory costs, human health costs, environmental costs and defensive expenditures.
References
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Journal ArticleDOI

Cancer statistics, 2012

TL;DR: The reduction in overall cancer death rates since 1990 in men and 1991 in women translates to the avoidance of about 1,024,400 deaths from cancer, which can be accelerated by applying existing cancer control knowledge across all segments of the population, with an emphasis on those groups in the lowest socioeconomic bracket.
Journal ArticleDOI

From the Centers for Disease Control and Prevention

TL;DR: This report summarizes the clinical features of these cases and the epidemiologic investigations by the Texas Department of Health and the New Jersey State Department of health and Senior Services, which indicated that a bat-associated variant of the rabies virus was responsible for infection in both cases.
Journal ArticleDOI

Epigenetic Transgenerational Actions of Endocrine Disruptors and Male Fertility

TL;DR: The ability of an environmental factor to reprogram the germ line and to promote a transgenerational disease state has significant implications for evolutionary biology and disease etiology.
Journal ArticleDOI

American Cancer Society Guidelines on Nutrition and Physical Activity for Cancer Prevention: Reducing the Risk of Cancer with Healthy Food Choices and Physical Activity

TL;DR: This committee presents one key recommendation for community action to accompany the four recommendations for individual choices to reduce cancer risk, recognizing that a supportive social environment is indispensable if individuals at all levels of society are to have genuine opportunities to choose healthy behaviors.
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