Induction of apoptosis in fibroblasts by c-myc protein
Citations
6,462 citations
4,150 citations
3,151 citations
Cites background from "Induction of apoptosis in fibroblas..."
...In addition to its well documented growth-promoting property, Myc was found to be a powerful inducer of apoptosis, especially under conditions of stress, genotoxic damage or depleted survival factor...
[...]
3,073 citations
2,796 citations
References
3,773 citations
3,256 citations
"Induction of apoptosis in fibroblas..." refers background in this paper
...It possesses a number of functional domains found in other proteins modulating transcription, specifically the leucine zipper characteristic of the Fos-Jun-CREB transcription factor families (Landschulz et al., 1988) and the basic-helix-loop-helix motif found in, for example, the MyoD and E box enhancer-binding proteins (Murre et al....
[...]
2,418 citations
2,235 citations
"Induction of apoptosis in fibroblas..." refers background in this paper
...grammed cell death pathway both before and after the commitment point in late G, ( Pardee, 1989 )....
[...]
...Constitutive Myc Expression Induces Apoptosis in Rat-l Cells Arrested by Various Means at Various Points in the Cell Cycle Fibroblast proliferation can be temporarily blocked in a number of mechanistically different ways whilst maintaining viability (reviewed in Pardee, 1989 )....
[...]
2,143 citations