Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors.
Citations
18,175Â citations
Cites background from "Induction of pluripotent stem cells..."
...We showed that induced pluripotent stem (iPS) cells can be generated from mouse embryonic fibroblasts (MEF) and adult mouse tail-tip fibroblasts by the retrovirus-mediated transfection of four transcription factors, namely Oct3/4, Sox2, c-Myc, and Klf4 (Takahashi and Yamanaka, 2006)....
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...Induction of iPS cells from mouse fibroblasts requires retroviruses with high transduction efficiencies (Takahashi and Yamanaka, 2006)....
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...Optimization of Retroviral Transduction for Generating Human iPS Cells Induction of iPS cells from mouse fibroblasts requires retroviruses with high transduction efficiencies (Takahashi and Yamanaka, 2006)....
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4,371Â citations
Cites background from "Induction of pluripotent stem cells..."
...By: Philbrick, Samuel Keywords: Stem cells [2] Pluripotency [3] Somatic cells [4] Differentation [5]...
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...edu/pages/generation-germline-competent-induced-pluripotent-stem-cells-2007-keisuke-okita-tomoko [2] https://embryo....
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References
15,555Â citations
"Induction of pluripotent stem cells..." refers background in this paper
...Human ES cells might be used to treat a host of diseases, such as Parkinson’s disease, spinal cord injury, and diabetes (Thomson et al., 1998)....
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8,144Â citations
"Induction of pluripotent stem cells..." refers background in this paper
...Embryonic stem (ES) cells, which are derived from the inner cell mass of mammalian blastocysts, have the ability to grow indefinitely while maintaining pluripotency and the ability to differentiate into cells of all three germ layers (Evans and Kaufman, 1981; Martin, 1981)....
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5,496Â citations
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"Induction of pluripotent stem cells..." refers methods in this paper
...129 background) was mated with an ICR mouse with the GFP transgene driven by the constitutive CAG promoter ( Niwa et al., 1991 )....
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4,721Â citations
"Induction of pluripotent stem cells..." refers background in this paper
...Somatic cells can be reprogrammed by transferring their nuclear contents into oocytes (Wilmut et al., 1997) or by fusion with ES cells (Cowan et al....
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...Somatic cells can be reprogrammed by transferring their nuclear contents into oocytes (Wilmut et al., 1997) or by fusion with ES cells (Cowan et al., 2005; Tada et al., 2001), indicating that unfertilized eggs and ES cells contain factors that can confer totipotency or pluripotency to somatic cells....
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