Inflammation and pain in skin and deep tissues
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22 citations
"Inflammation and pain in skin and d..." refers background or methods in this paper
...However, the existence of secondary hyperalgsia as a consequence of UVB irradiation has always been controversial and has been confirmed only by some groups (Davies et al., 2011; Gustorff et al., 2013; Weerasinghe et al., 2014)....
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...Even though the UVB model has been well characterized both in animals and humans (Bishop et al., 2009; Bishop et al., 2007; Davies et al., 2011; Gustorff et al., 2013; Harrison et al., 2004), the presence of secondary hyperalgesia in this model is still controversial....
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...Even though the UVB model has been well characteriz ed both in animals and humans (Bishop et al., 2009; Bishop et al., 2007; Davies et al., 2011 ; Gustorff et al., 2013; Harrison et al., 2004), th e presence of secondary hyperalgesia in this model is still controversial....
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...45 conducted by Davis and collaborators in rats provid es evidence that the secondary hyperalgesic area induce by UVB-irradiation in the plantar hind paw w as enhanced and prolonged by heat rekindling (Davies et al., 2011; Weerasinghe et al., 2014)....
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...The study 45 conducted by Davis and collaborators in rats provides evidence that the secondary hyperalgesic area induce by UVB-irradiation in the plantar hind paw was enhanced and prolonged by heat rekindling (Davies et al., 2011; Weerasinghe et al., 2014)....
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20 citations
"Inflammation and pain in skin and d..." refers background in this paper
...Burn and freeze injury models are frequently used in humans to induce either primary or secondary hyperalgesia by pplication of warm (52°C/30-45 s) or cold (- 28°C) stimuli, respectively (Zhang and Ren 2011)....
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...Several studies have confirmed that capsaicin induces flare reaction, hyperalgesia and allodynia in the area of pplication and in the adjacent area (Bishop et al., 2009; Zhang and Ren 2011)....
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...…experimental pain models are the most used on s, mostly because of the easy access to the skin (Staahl and Drewes 2004), and a widespread range of inflammatory substances and irritants can be used to produce temporary and reversible tissues injury and hyperalgesia in the skin (Zhang and Ren 2011)....
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19 citations
"Inflammation and pain in skin and d..." refers background in this paper
...The process of nociception refers to the recognition of a noxious stimulus from a nociceptor and its transmission to the brain through peripheral and central neurons (Holdcroft and Jaggar 2005; Kidd and Urban 2001; Woolf 1983)....
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...The term inflammatory pain indicates the pain originating from a tissue injury, irritation or infection, which usually lead to inflammation (Holdcroft and Jaggar 2005)....
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...The symptoms of inflammation consist of warmth and redness of the skin, along with swelling and pain (Holdcroft and Jaggar 2005)....
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...The symptoms of inflammation consist of wa rmth and redness of the skin, along with swelling and pain (Holdcroft and Jaggar 2005)....
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...Inflammatory pain and inflammation are mediated by release of inflammatory mediators, called also “inflammatory soup”, from damaged cells that increase the sensitivity of nociceptors to noxious thermal or mechanical stimuli (Basbaum et al., 2009; Holdcroft and Jaggar 2005; Huang et al., 2006)....
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18 citations
"Inflammation and pain in skin and d..." refers background in this paper
...Several studies have reported e rythema and skin pallor after application of EMLA under occlusive dressing probably as a consequ ence of vasoactive properties of both lidocaine and prilocaine (Tahir et al., 2006)....
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...Several studies have reported erythema and skin pallor after application of EMLA under occlusive dressing probably as a consequence of vasoactive properties of both lidocaine and prilocaine (Tahir et al., 2006)....
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16 citations
"Inflammation and pain in skin and d..." refers background or result in this paper
...These reactions are present in a variety of chronic inflammatory states, such as rheumatoid arthritis, and can be used in healthy volunteers to study the pain system under well controlled settings (Handwerker and Arendt-Nielsen 2013; Staahl and Drewes 2004)....
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...The exercises-induced DOMS is a well-established and long- asting model and resembles some characteristics seen in several clinical conditions in musculoskeletal pain or ischemic muscle pain (Handwerker and Arendt-Nielsen 2013; Nie et al., 2005)....
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