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Journal ArticleDOI

Influence of age and splanchnic nerve on glucagon-induced changes of adrenomedullary catecholamine content and blood glucose level in the avian group

01 Sep 1991-Journal of Comparative Physiology B-biochemical Systemic and Environmental Physiology (Springer Nature)-Vol. 161, Iss: 5, pp 532-536

TL;DR: The results indicate that the splanchnic nerve regulates release and/or resynthesis of CA induced by glucagon and that aging modulates glucagon-induced changes of catecholamine (CA) content.

AbstractGlucagon (0.1 mg · 100 g body wt-1) increased norepinephrine (NE) content in adult pigeon (31%) and parakeet (58%), decreased NE content in the adrenal medulla of newly-hatched pigeon (36%), parakeet (52%), and crow (44%) 0.5 h after treatment. Epinephrine (E) content decreased to 26% and 59% of control values, respectively, in newly-hatched pigeon and parakeet 0.5 h after treatment. Glucagon produced hyperglycemia irrespective of age and species. The results indicate that aging modulates glucagon-induced changes of catecholamine (CA) content. In the innervated (I) adrenal gland of pigeon, glucagon caused a 31% increase of NE content 0.5 h after injection, a 46% decrease of NE content 12 h after injection, and a 192% increase of NE 24 h after injection. In the I gland of pigeons, glucagon also caused a 61% decrease of E content 4 h after injection, and brought about a 100% increase of E 24 h after injection. Glucagon-induced changes of CA content differ significantly between the I and denervated (D) glands. The results indicate that the splanchnic nerve regulates release and/or resynthesis of CA induced by glucagon.

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Citations
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01 Jan 2001
TL;DR: Although progress has been made, it is apparent that research on the avian adrenal medulla still lags behind work on the mammalian organ.
Abstract: The purpose of this review is to explore the world literature on the avian adrenal medulla from the last 20 years. Unlike the mammalian adrenal medulla, the adrenal gland in birds has chromaffin cells mixed with cortical cells. Studies have investigated the ultrastructure (both transmission and scanning electron microscopy), biochemistry, and physiology (partic- ularly interactions with other endocrine glands) of the avian adrenal medulla. Although progress has been made, it is apparent that research on the avian adrenal medulla still lags behind work on the mammalian organ.

14 citations


References
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Abstract: Originally published in 1959, this classic volume has had a major impact on generations of statisticians. Newly issued in the Wiley Classics Series, the book examines the basic theory of analysis of variance by considering several different mathematical models. Part I looks at the theory of fixed-effects models with independent observations of equal variance, while Part II begins to explore the analysis of variance in the case of other models.

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04 May 1984-Science
TL;DR: Together these agents appear to determine the complex physiologic responses to a variety of stressors.
Abstract: Stress stimulates several adaptive hormonal responses. Prominent among these responses are the secretion of catecholamines from the adrenal medulla, corticosteroids from the adrenal cortex, and adrenocorticotropin from the anterior pituitary. A number of complex interactions are involved in the regulation of these hormones. Glucocorticoids regulate catecholamine biosynthesis in the adrenal medulla and catecholamines stimulate adrenocorticotropin release from the anterior pituitary. In addition, other hormones, including corticotropin-releasing factor, vasoactive intestinal peptide, and arginine vasopressin stimulate while the corticosteroids and somatostatin inhibit adrenocorticotropin secretion. Together these agents appear to determine the complex physiologic responses to a variety of stressors.

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TL;DR: A fluorometric hydroxyindole assay method for a wide range of catecholamines and related compounds has been developed based on iodine oxidation, alkaline rearrangement, and subsequent measurement of the fluorescence of the final solution at an acid pH.
Abstract: A fluorometric hydroxyindole assay method for a wide range of catecholamines and related compounds has been developed based on iodine oxidation, alkaline rearrangement, and subsequent measurement of the fluorescence of the final solution at an acid pH. The structural requirements for the hydroxyindole reaction have been examined. The use of specific conditions for each compound at each stage of the reaction has resulted in increased sensitivity, selectivity, and reproducibility, while the use of one basic method for a wide variety of compounds is an advantage for laboratory applications.

697 citations


"Influence of age and splanchnic ner..." refers methods in this paper

  • ...NE and E were extracted, purified, and estimated fluorometrically (Laverty and Taylor 1968 ; Cox and Perhach 1973)....

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