Journal ArticleDOI
Inhibition of influenza virus internalization by (-)-epigallocatechin-3-gallate.
Meehyein Kim,Soyeon Kim,Hyewon Lee,Jin Soo Shin,Pilho Kim,Young-Sik Jung,Hyeongseop Jeong,Jae-Kyung Hyun,Chong-Kyo Lee +8 more
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TLDR
It is suggested that the anti-influenza viral efficacy of EGCG is attributable to damage to the physical properties of the viral envelope and partial inhibition of the NA surface glycoprotein.About:
This article is published in Antiviral Research.The article was published on 2013-11-01. It has received 98 citations till now. The article focuses on the topics: Viral entry & Viral membrane.read more
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Flavonoids: promising natural compounds against viral infections.
TL;DR: The evidence for antiviral activity of different flavonoids is summarized, highlighting, where investigated, the cellular and molecular mechanisms of action on viruses and future perspectives on therapeutic applications of flavonoid against viral infections are presented.
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A Small Molecule Inhibits Virion Attachment to Heparan Sulfate- or Sialic Acid-Containing Glycans
Che C. Colpitts,Luis M. Schang +1 more
TL;DR: This study shows that it is possible to develop a small molecule antiviral or microbicide active against the two largest groups of human viruses: those that bind to glycosaminoglycans and those thatbind to sialoglycANS.
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Anti-influenza Viral Effects of Honey In Vitro: Potent High Activity of Manuka Honey
TL;DR: The results showed that honey, in general, and particularly manuka honey, has potent inhibitory activity against the influenza virus, demonstrating a potential medicinal value.
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Therapeutic Potential of Epigallocatechin Gallate Nanodelivery Systems
TL;DR: A comprehensive review of studies currently available on the encapsulation of EGCG by means of nanocarriers will be addressed, supporting the notion that this molecule has several benefits in fighting cancer, heart diseases, diabetes, and obesity, among others.
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(-)-Epigallocatechin-3-gallate inhibits entry of hepatitis B virus into hepatocytes.
TL;DR: Results show that the green tea-derived molecule EGCG potently inhibits HBV entry and could be used in prevention of HBV reinfection.
References
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Universal primer set for the full-length amplification of all influenza A viruses.
TL;DR: The resultant primer set is suitable for all influenza A viruses to generate full-length cDNAs, to subtype viruses, to sequence their DNA, and to construct expression plasmids for reverse genetics systems.
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Beneficial Effects of Green Tea—A Review
TL;DR: Although all the evidence from research on green tea is very promising, future studies are necessary to fully understand its contributions to human health, and advise its regular consumption in Western diets, in which green tea consumption is nowadays limited and sporadic.
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A DNA transfection system for generation of influenza A virus from eight plasmids
TL;DR: An eight-plasmid DNA transfection system for the rescue of infectious influenza A virus from cloned cDNA facilitates the design and recovery of both recombinant and reassortant influenza A viruses, and may also be applicable to the recovery of other RNA viruses entirely from cloning cDNA.
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Inhibition of carcinogenesis by tea.
TL;DR: Tea has received a great deal of attention because tea polyphenols are strong antioxidants, and tea preparations have inhibitory activity against tumorigenesis, but epidemiological studies have not yielded clear conclusions concerning the protective effects of tea consumption against cancer formation in humans.
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Infectious entry pathway of influenza virus in a canine kidney cell line
TL;DR: The experiments suggest that fowl plague virus enters MDCK cells by endocytosis in coated pits and coated vesicles and is transported to the lysosome where the low pH initiates a fusion reaction ultimately resulting in the transfer of the genome into the cytoplasm.