Inhibition of interleukin-33 signaling attenuates the severity of experimental arthritis.
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...IL-33 is also expressed in rheumatoid arthritis synovium and implicated in the enhancement of arthritis in rodent...
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925 citations
Cites background from "Inhibition of interleukin-33 signal..."
...IL-33 and ST2 are detected in the synovium of patients with rheumatoid arthriti...
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Cites background from "Inhibition of interleukin-33 signal..."
...IL-33 [previously known as nuclear factor from high endothelial venule or NF-HEV (4, 5)], is a chromatin-associated nuclear cytokine from the IL-1 family (6, 7), which has been linked to important diseases (8–10), including asthma (11), rheumatoid arthritis (12, 13), ulcerative colitis (14), and cardiovascular diseases (15)....
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...IL-33 has been shown to play important roles in mouse models of rheumatoid arthritis (12, 13) and to orchestrate neutrophil migration into the joints (41)....
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