Journal ArticleDOI
Interaction of detergents with lipid vesicles
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This article is published in Biochimica et Biophysica Acta.The article was published on 1995-07-17. It has received 201 citations till now.read more
Citations
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Journal ArticleDOI
Interaction of membrane proteins and lipids with solubilizing detergents.
TL;DR: The nature of detergent binding by the membrane from a noncooperative to a cooperative interaction already below the critical micellar concentration is considered and it is concluded that in general binding as a monolayer ring, rather than as a micelle, is the most probable mechanism.
Journal ArticleDOI
Insolubility of lipids in Triton X-100: physical origin and relationship to sphingolipid/cholesterol membrane domains (rafts)
Erwin London,Deborah A. Brown +1 more
TL;DR: Detergent insolubility is an invaluable tool for studying cellular rafts and characterizing their composition and can depend on lipid composition, detergent and temperature.
Journal ArticleDOI
Lipid vesicles and other colloids as drug carriers on the skin.
TL;DR: Sufficiently stable ultra-adaptable carriers, therefore, can ensure targeted drug delivery deep below the application site, and allow highly efficient and well-tolerated drug targeting into the skin proper by means of highly adaptable drug carriers.
Journal ArticleDOI
Surface active drugs: self-association and interaction with membranes and surfactants. Physicochemical and biological aspects
TL;DR: This review focuses on the self-aggregation properties of drugs, as well as on their interaction with membranes, and it is seen that drug-membrane interactions are analogous to the interactions between membranes and classical detergents.
Journal ArticleDOI
Liposomes: technologies and analytical applications.
Aldo Jesorka,Owe Orwar +1 more
TL;DR: This review provides information about new developments in some of the most actively researched liposome-related topics, such as drug and gene delivery and immunoassays.
References
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Journal ArticleDOI
Solubilization of membranes by detergents
Ari Helenius,Kai Simons +1 more
TL;DR: This review focuses on work that deals with the mechanisms of detergent action in membrane solubilization including properties of detergents model lipid systems and detergent-protein interactions; in addition a possible sequence of events when deterGents interact with biological membranes receives attention.
Journal ArticleDOI
Lipid polymorphism and the functional roles of lipids in biological membranes.
Pieter R. Cullis,B. de Kruijff +1 more
TL;DR: The possible functional roles of lipids are reviewed in terms of previous models such as the fluid mosaic model of Singer and Nicolson or the earlier unit membrane model so that the requirement for an alternative approach becomes apparent.
Book
Liposomes: From Physics to Applications
TL;DR: Part 1 General Introduction to Liposomes: Chemistry of lipids and liposomes and applications in Basic Sciences and Pharmacology and Medicine.
Book
Spin Labeling: Theory And Applications
TL;DR: This special topics volume represents a complete update on new theoretical aspects and applications of the spin-label method and includes an IBM-compatible diskette supplied by David Schneider and Jack Freed which contains fast, accurate, ready-to-use software for slow-motion simulations.