Interaction of FUS and HDAC1 regulates DNA damage response and repair in neurons
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...…has been linked to various neurological disorders, and we previously described the formation of DNA lesions, particularly DNA DSBs, to be an apical neurotoxic event in several mouse models of neurodegeneration (Dobbin et al., 2013; Kim et al., 2008; Madabhushi et al., 2014; Wang et al., 2013)....
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...accrual of DNA damage has been linked to various neurological disorders, and we previously described the formation of DNA lesions, particularly DNA DSBs, to be an apical neurotoxic event in several mouse models of neurodegeneration (Dobbin et al., 2013; Kim et al., 2008; Madabhushi et al., 2014; Wang et al., 2013)....
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