International collaborative research for pediatric and neonatal lung injury: the example of an ESPNIC initiative to validate definitions and formulate future research questions
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Cites background from "International collaborative researc..."
...The Berlin definition does not include specific pediatric criteria but appears to have a good diagnostic performance in children younger than 24 months of age.(19) Children of all ages can be affected by and develop ARDS, including full-term newborns, but its prevalence increases with age; additionally, significant differences in prevalence are rarely observed between genders....
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2 citations
Cites background from "International collaborative researc..."
...Dear Sir, It was with great interest and pleasure that we read the Letter to the Editor entitled ‘‘International collaborative research for pediatric and neonatal lung injury: the example of an ESPNIC initiative to validate definitions and formulate future research questions’’ by Daniele De Luca et al.1 The authors commented that the European Society for Pediatric and Neonatal Intensive Care (ESPNIC) published the first validation of the acute respiratory distress syndrome (ARDS) Berlin Definition (BD) in early childhood.2 Members of the ESPNIC Respiratory Section performed a retrospective international (Italy, Spain, France, Austria, and the Netherlands) multicenter study including children aged between 30 days and 18 months with ARDS according to the American-European Consensus Conference (AECC) criteria.3 It elegantly addresses our concerns on the applicability of BD in pediatrics when we described the evolution of ARDS definitions.4 A time lapse between the two publications prevented exact connections between them; now is the opportunity to do so....
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...In summary, we congratulate De Luca et al.2 for their timely study, and thank them for their comments....
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...It was with great interest and pleasure that we read the Letter to the Editor entitled ‘‘International collaborative research for pediatric and neonatal lung injury: the example of an ESPNIC initiative to validate definitions and formulate future research questions’’ by Daniele De Luca et al.(1) The authors commented that the European Society for Pediatric and Neonatal Intensive Care (ESPNIC) published the first validation of the acute respiratory distress syndrome (ARDS) Berlin Definition (BD) in early childhood....
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References
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"International collaborative researc..." refers methods in this paper
...The Brazilian Pediatric ARDS Study Group6 performed a prospective, multicentre cohort study from March to September of 2013, which aimed: (1) to evaluate the prevalence of ARDS; (2) to determine risk factors for ARDS; and (3) to evaluate whether the use of BD in critically ill children can better discriminate the severity of the disease compared with the AECC definition....
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1,074 citations
"International collaborative researc..." refers background in this paper
...In addition, concerns were expressed regarding the application of the new Berlin criteria to the pediatric population, as there were no children in their original development population.(4,5) This is the reason why the Respiratory Failure Section of ESPNIC started the above-mentioned project to evaluate the reliability of the new Berlin definition in a homogeneous and adequately large pediatric population....
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259 citations
"International collaborative researc..." refers methods in this paper
...Both are practical tools that have proven to be helpful in clinical practice and research.(2,4,7,8) However, the ESPNIC collaborative work validating the new Berlin criteria for pediatric ARDS patients has some limitations that have already been pointed out....
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203 citations
"International collaborative researc..." refers background in this paper
...In fact, infants and toddlers present peculiarities regarding lung development, respiratory system mechanics, and co-morbidities, which are responsible for the peculiar epidemiology and prognosis of ARDS in these patients.(6) The main results demonstrated that the new Berlin definition has the same reliability both for the pediatric and adult patients in terms of mortality and need for extracorporeal life support....
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...The project focused on the early pediatric age (range: 30 days to 18 months), since especially at this age, the syndrome is distinctly different from ARDS in adults.(2,6) In fact, infants and toddlers present peculiarities regarding lung development, respiratory system mechanics, and co-morbidities, which are responsible for the peculiar epidemiology and prognosis of ARDS in these patients....
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