Intracortical and Thalamocortical Connections of the Hand and Face Representations in Somatosensory Area 3b of Macaque Monkeys and Effects of Chronic Spinal Cord Injuries.
Citations
109 citations
Cites background from "Intracortical and Thalamocortical C..."
...In fact, there is little anatomical evidence that the face-elicited activity in SI is mediated by the growth of new cortico-cortical projections: Very few axons cross the face–hand boundary in SI of intact animals (see [57] for analogous results in humans revealed with neuroimaging) and deafferentation of the hand region does not result in any measurable increase in these boundary-crossing projections [58]....
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97 citations
Cites background from "Intracortical and Thalamocortical C..."
...…more limited than initially thought, and that instead the functional changes previously observed in S1 following input loss could be attributed to reorganisation in sub-cortical areas in the afferent pathway, principally the brainstem (Jain et al., 1998; Kambi et al., 2014; Chand and Jain, 2015)....
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70 citations
Cites background from "Intracortical and Thalamocortical C..."
...It has been suggested that the initial remapping triggered by deprivation will become refined by inputs due to daily hand usage involving compensatory behaviours (Churchill et al., 1998; Elbert et al., 1997)....
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63 citations
Cites background from "Intracortical and Thalamocortical C..."
...However, a recent definitive study showed that in monkeys with chronic lesions of the dorsal column of spinal cord that had resulted in large-scale map reorganization of hand and face representations in area 3b, nevertheless showed a striking absence of new intracortical projections across the hand–face border (Chand and Jain 2015)....
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31 citations
References
259 citations
"Intracortical and Thalamocortical C..." refers background or result in this paper
...These locations correspond to representations of D1 and chin in the VP nucleus (Jones and Friedman, 1982; Kaas et al., 1984; Darian-Smith et al., 1990; Burton and Fabri, 1995; Padberg et al., 2009)....
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...Normal thalamocortical connections and the somatotopy in the VP nucleus of thalamus have been described by many laboratories, and our data conform to previous reports (Jones and Friedman, 1982; Darian-Smith et al., 1990; Krubitzer and Kaas, 1992; Padberg et al., 2009; Cerkevich et al., 2013)....
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246 citations
"Intracortical and Thalamocortical C..." refers background in this paper
...Axonal sprouting that causes reorganization likely takes place at subthalamic levels. the thalamus (Jones and Pons, 1998; Kaas et al., 1999; Jain et al., 2008), and cuneate nucleus of the brainstem (Kambi et al., 2014)....
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...Role of intrinsic connections in plasticity Intrinsic connections likely contribute to the brain reorganization (Burton and Fabri, 1995; Jones and Pons, 1998)....
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...…afferents from VPM into the deafferented hand area, or VPL into the face region of area 3b. Previously, extensive shrinkage of VP nucleus has been reported in monkeys with dorsal root sections, which was proposed to be a likely mediator of large-scale brain plasticity (Jones and Pons, 1998)....
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205 citations
"Intracortical and Thalamocortical C..." refers background in this paper
...Intrinsic connections restricted to functional compartments have been observed in other systems, including visual, auditory, and motor cortex (Huntley and Jones, 1991; Yoshioka et al., 1996; Read et al., 2001; Ahmed et al., 2012)....
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195 citations
"Intracortical and Thalamocortical C..." refers background in this paper
...…of intact chin inputs into the deafferented hand region of primary somatosensory area 3b, second somatosensory area S2, parietal ventral area PV (Jain et al., 1997, 1998a; Kaas et al., 2008; Tandon et al., 2009), ventroposterior (VP) nucleus of Received May 26, 2015; revised Aug. 24, 2015;…...
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...We extend these observations and show that chin representation also has only few connections across the hand– face border, which is important because it is the chin representation that expands as a result of massive deafferentations (Pons et al., 1991; Jain et al., 1997, 2008)....
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193 citations
"Intracortical and Thalamocortical C..." refers background or result in this paper
...These locations correspond to representations of D1 and chin in the VP nucleus (Jones and Friedman, 1982; Kaas et al., 1984; Darian-Smith et al., 1990; Burton and Fabri, 1995; Padberg et al., 2009)....
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...Normal thalamocortical connections and the somatotopy in the VP nucleus of thalamus have been described by many laboratories, and our data conform to previous reports (Jones and Friedman, 1982; Darian-Smith et al., 1990; Krubitzer and Kaas, 1992; Padberg et al., 2009; Cerkevich et al., 2013)....
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