Intraventricular administration of neuropeptide S has reward-like effects.
Citations
88 citations
Cites background from "Intraventricular administration of ..."
...In addition to its strong influence on stress-induced anxiety-related behavior, the NPS and its NPSR have been shown to be involved in many other physiological and pathological processes including depression-like behavior [306], drug seeking [312], food intake [313], respiratory function [314], asthma/atopy [315-318] and inflammatory bowel disease [319]....
[...]
79 citations
Cites background from "Intraventricular administration of ..."
...NPS is an excellent candidate for this purpose, as, although reward-like effects have been reported by others (Cao et al, 2011), NPS does not act as a GABAA receptor agonist....
[...]
56 citations
37 citations
29 citations
References
2,042 citations
"Intraventricular administration of ..." refers background in this paper
..., 2005), while behavioral sensitization depends on their actions in the ventral tegmental area (Kalivas and Stewart, 1991; Kalivas and Weber, 1988; Vezina and Stewart, 1990)....
[...]
1,387 citations
"Intraventricular administration of ..." refers background in this paper
...Because dopamine transmission occurring in the medial part of the ventral striatum plays a critical role in reward seeking (Ikemoto, 2007; Shin et al., 2010), the medial ventral striatum may play a critical role in cue-assisted self-administration of NPS....
[...]
474 citations
"Intraventricular administration of ..." refers background in this paper
...In addition, the fact that intraventricular NPS promotes locomotor activity and wakefulness (Xu et al., 2004) makes it unclear whether increased lever pressing was due to enhanced seeking or “general” arousal....
[...]
...Neuropeptide S (NPS) is a recently identified endogenous ligand of an orphan G protein coupled receptor (Xu et al., 2004)....
[...]
426 citations
391 citations
"Intraventricular administration of ..." refers background in this paper
...…to be expressed throughout the brain (Leonard and Ring, 2011; Xu et al., 2007), including in the regions that are associated with reward processes (Ikemoto, 2010): the ventral tegmental area, olfactory tubercle, bed nucleus of stria terminalis, diagonal band, paraventricular thalamic nucleus,…...
[...]
..., 2007), including in the regions that are associated with reward processes (Ikemoto, 2010): the ventral tegmental area, olfactory tubercle, bed nucleus of stria terminalis, diagonal band, paraventricular thalamic nucleus, preoptic area, lateral and posterior hypothalamic areas, periaqueductal gray, median and dorsal raphe nuclei and parabrachial nucleus....
[...]