Investigating the prevalence of complex fiber configurations in white matter tissue with diffusion magnetic resonance imaging.
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...Second, the fiber orientations are selected as the distinct peaks of the fODF with an amplitude exceeding a user-defined threshold (Jeurissen et al., 2013)....
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...Finally, probabilistic streamline fiber tractography was performed to investigate the effect of denoising on the tractogram using the MRtrix software package (Jeurissen et al., 2013; Tournier et al., 2012)....
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1,015 citations
Cites background or methods from "Investigating the prevalence of com..."
...It also complicates the interpretation of DTI metrics, which are often suggested for use as surrogate markers of WM ‘integrity’ (Jones, 2010; Vos et al., 2012; Wheeler-Kingshott and Cercignani, 2009; Jeurissen et al., 2013)....
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...First, all unique maxima exceeding a threshold of 0.3 relative to the largest peak were extracted from the fODFs by means of the optimisation procedure described in Jeurissen et al. (2013)....
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...surrogate markers of WM ‘integrity’ (Jones, 2010; Vos et al., 2012; Wheeler-Kingshott and Cercignani, 2009; Jeurissen et al., 2013)....
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876 citations
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...Previous research suggested that at typical DWimaging resolutions, around one-third of white matter voxels in the brain contain such complex architecture (Behrens et al., 2007); however,more recent evidence indicates that this figuremay be as high as 90% (Jeurissen et al., 2012)....
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..., 2007); however,more recent evidence indicates that this figuremay be as high as 90% (Jeurissen et al., 2012)....
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466 citations
Cites background from "Investigating the prevalence of com..."
...…to noise, and the tensor model is unable to recover multiple diffusion orientations in single voxels, making it impossible to reconstruct tracts passing through brain regions with complex fiber architecture, also referred to as “crossing fibers” (Tournier et al., 2011; Jeurissen et al., 2013)....
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References
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"Investigating the prevalence of com..." refers methods in this paper
...Diffusion-weighted (DW) magnetic resonance imaging (MRI) is a unique noninvasive method for probing tissue microstructure in vivo, based on the random thermal motion of water molecules [Stejskal and Tanner, 1965]....
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"Investigating the prevalence of com..." refers methods in this paper
...Next, the T1-weighted image was registered to the FA image using 3D nonrigid b-spline-based registration with Mattes mutual information as the similarity measure [Klein et al., 2010; Mattes et al., 2001] (Fig....
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3,315 citations