Investigation on cell proliferation with a new antibody against thymidine kinase 1.
Citations
193 citations
Cites background from "Investigation on cell proliferation..."
...Wang and colleagues [78] have developed a polyclonal anti-TK1 antibody and demonstrated cell cycle-dependent expression of the enzyme....
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74 citations
72 citations
70 citations
Cites background from "Investigation on cell proliferation..."
...The presence of TK1 positive cells could be demonstrated in both, normal and malignant tissue [11]....
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70 citations
Cites methods from "Investigation on cell proliferation..."
...Although immunochemical methods have been reported, a highly sensitive but convenient approach for routine measurement of serum TK1 in haematological malignancies has not been forthcoming [16-19] ....
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References
280 citations
"Investigation on cell proliferation..." refers background in this paper
...Recently, also cell cycle related gene expression such as the expression of the p53 tumor suppressor gene has been the subject of studies relating to the prognosis of malignancies [4,16,30]....
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207 citations
"Investigation on cell proliferation..." refers background in this paper
...We have developed a polyclonal anti-TK1 antibody against a synthetic peptide from the C-terminus of human TK1....
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206 citations
"Investigation on cell proliferation..." refers methods in this paper
...In clinical investigations, mitotic count, 3H-thymidine labeling index, bromodeoxyuridine (BrdU) incorporation, expression of Ki-67, proliferating cell nuclear antigen, and cyclins, as well as measurement of S-phase by means of DNA flow cytometry have been used in the assessment of cell proliferation [5,8,17,22,33,36,37]....
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189 citations
"Investigation on cell proliferation..." refers methods in this paper
...In clinical investigations, mitotic count, 3H-thymidine labeling index, bromodeoxyuridine (BrdU) incorporation, expression of Ki-67, proliferating cell nuclear antigen, and cyclins, as well as measurement of S-phase by means of DNA flow cytometry have been used in the assessment of cell proliferation [5,8,17,22,33,36,37]....
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