Investigation on cell proliferation with a new antibody against thymidine kinase 1.
Citations
193 citations
Cites background from "Investigation on cell proliferation..."
...Wang and colleagues [78] have developed a polyclonal anti-TK1 antibody and demonstrated cell cycle-dependent expression of the enzyme....
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Cites background from "Investigation on cell proliferation..."
...The presence of TK1 positive cells could be demonstrated in both, normal and malignant tissue [11]....
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70 citations
Cites methods from "Investigation on cell proliferation..."
...Although immunochemical methods have been reported, a highly sensitive but convenient approach for routine measurement of serum TK1 in haematological malignancies has not been forthcoming [16-19] ....
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References
92 citations
"Investigation on cell proliferation..." refers background in this paper
...Overexpression of the E2F gene products induces quiescent cells to enter S-phase combined with overexpression of TK1 [27]....
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83 citations
"Investigation on cell proliferation..." refers background in this paper
...chemical studies that the cell cycle related increase in TK1 activity is combined with increased expression of mRNA as well as of the TK1 protein [2, 14,19,25,32,35,38]....
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80 citations
"Investigation on cell proliferation..." refers background in this paper
...The intracellular localizations of various viral TKs and as well the other deoxnucleoside kinases were recently reinvestigated and nuclear forms of these enzymes were reported [6,13,18]....
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...In studies with fluorescent protein fused with human or viral TK1, cytoplasmic fluorescence but also low level of fluorescence in the cell nuclei was found [18]....
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71 citations
"Investigation on cell proliferation..." refers methods in this paper
...The cell cycle composition was determined by DNA flow cytometry as described previously [3]....
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69 citations