Is there a role for carbohydrate restriction in the treatment and prevention of cancer
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13 citations
Cites background from "Is there a role for carbohydrate re..."
...One of the characteristic features of malignant tumors is their ability to reprogramme glucose metabolism from the oxidative phosphorylation pathway to glucose aerobic glycolysis (Warburg’s effect), which represents a selective growth advantage [27, 28]....
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13 citations
Cites background from "Is there a role for carbohydrate re..."
...Carbohydrate-restricted diets have also been suggested as a promising therapeutic approach in tumors [4,5,6]....
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12 citations
12 citations
Additional excerpts
...catabolic processes such as autophagy [1144, 1145]....
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12 citations
References
51,099 citations
"Is there a role for carbohydrate re..." refers background in this paper
..., a pathological capability common to most, if not all, cancer cells [39]....
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9,282 citations
"Is there a role for carbohydrate re..." refers background in this paper
...Inflammation is a wellestablished driver of early tumorigenesis and accompanies most, if not all cancers [148]....
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4,361 citations
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"Is there a role for carbohydrate re..." refers background in this paper
...As indicated in Figure 2, restriction of dietary CHOs would counteract this signalling cascade by normalizing glucose and insulin levels in subjects with metabolic syndrome, in this way acting similar to calorie restriction/fasting [61,62]....
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