Journal ArticleDOI
Isolation and identification of mosquito larvicidal compound from Abutilon indicum (Linn.) Sweet
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Results of this study show that the petroleum ether extract of A. indicum may be considered as a potent source and β-sitosterol as a new natural mosquito larvicidal agent.Abstract:
Larvicidal activity of crude hexane, ethyl acetate, petroleum ether, acetone and methanol extracts of five medicinal plants, Abutilon indicum, Aegle marmelos, Euphorbia thymifolia, Jatropha gossypifolia and Solanum torvum were assayed for their toxicity against the early fourth-instar larvae of Culex quinquefasciatus. The larval mortality was observed after 24 h exposure. All extracts showed moderate larvicidal effects; however, the highest larval mortality was found in petroleum ether extract of A. indicum. In the present study, bioassay-guided fractionation of A. indicum led to the separation and identification of a β-sitosterol as a potential new mosquito larvicidal compound with LC50 value of 11.49, 3.58 and 26.67 ppm against Aedes aegypti L, Anopheles stephensi Liston and C. quinquefasciatus Say (Diptera: Culicidae), respectively. 1H NMR, 13C NMR and mass spectral data confirmed the identification of the active compound. β-sitosterol has been recognized as the active ingredient of many medicinal plant extracts. All the crude extracts when screened for their larvicidal activities indicated toxicity against the larvae of C. quinquefasciatus. This article reports the isolation and identification of the β-sitosterol as well as bioassay data for the crude extracts. There are no reports of β-sitosterol in the genus A. indicum, and their larvicidal activities are being evaluated for the first time. Results of this study show that the petroleum ether extract of A. indicum may be considered as a potent source and β-sitosterol as a new natural mosquito larvicidal agent.read more
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Plant extracts as potential mosquito larvicides
TL;DR: The current state of knowledge on phytochemical sources and mosquitocidal activity, their mechanism of action on target population, variation of their larvicidal activity according to mosquito species, instar specificity, polarity of solvents used during extraction, nature of active ingredient and promising advances made in biological control of mosquitoes by plant derived secondary metabolites have been reviewed.
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Larvicidal activity of synthesized silver nanoparticles using Eclipta prostrata leaf extract against filariasis and malaria vectors
TL;DR: The results suggest that the synthesized AgNPs have the potential to be used as an ideal eco-friendly approach for the control of the Culex tritaeniorhynchus and A. subpictus vectors.
Journal ArticleDOI
The Story of Beta-sitosterol-A Review
TL;DR: Phytosterols are a subgroup of the steroids, as an important class of bioorganic molecules, widespread in plants, animals, marines as well as fungi and have similarity to cholesterol in structure.
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Larvicidal potential of medicinal plant extracts against Anopheles subpictus Grassi and Culex tritaeniorhynchus Giles (Diptera: Culicidae).
Chinnaperumal Kamaraj,Asokan Bagavan,Abdul Abdul Rahuman,A. Abduz Zahir,Gandhi Elango,G. Pandiyan +5 more
TL;DR: Results suggest that the leaf petroleum ether, flower methanol extracts of C. auriculata, leaf and seed methanl extracts of S. torvum and leaf hexane extract of V. negundo have the potential to be used as an ideal eco-friendly approach for the control of the A. subpictus and C. tritaeniorhynchus mosquito vector.
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Larvicidal activity of saponin from Achyranthes aspera against Aedes aegypti and Culex quinquefasciatus (Diptera: Culicidae).
TL;DR: The first report on the mosquito larvicidal activity of the saponin from the ethyl acetate extract of A. aspera is reported, which is an environmentally safe measure to control the vector of dengue and lymphatic filariasis.
References
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Journal ArticleDOI
Larvicidal effects of various essential oils against Aedes, Anopheles, and Culex larvae (Diptera, Culicidae).
Abdelkrim Amer,Heinz Mehlhorn +1 more
TL;DR: The oils of 41 plants were evaluated for their effects against third-instar larvae of Aedes aegypti, Anopheles stephensi and Culex quinquefasciatus and induced 100% mortality after 24 h, or even after shorter periods.
Journal ArticleDOI
Chemopreventive and adjuvant therapeutic potential of pomegranate (Punica granatum) for human breast cancer.
Nam Deuk Kim,Rajendra G. Mehta,Weiping Yu,Ishak Neeman,Talia Livney,Akiva Amichay,Donald Poirier,Paul J. Nicholls,Andrew James Kirby,Wenguo Jiang,Robert E. Mansel,Cheppail Ramachandran,Thangaiyan Rabi,Boris Kaplan,Ephraim Philip Lansky +14 more
TL;DR: The findings suggest that clinical trials to further assess chemopreventive and adjuvant therapeutic applications of pomegranate in human breast cancer may be warranted.
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