Citations
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Conformational states of a bacterial α2-macroglobulin resemble those of human complement C3.
David Neves,David Neves,Leandro F. Estrozi,Leandro F. Estrozi,Viviana Job,Viviana Job,Frank Gabel,Frank Gabel,Guy Schoehn,Andréa Dessen,Andréa Dessen +10 more
TL;DR: Structurally characterized ECAM is an elongated, flexible molecule with overall similarities to C3 in its inactive form; activation by methylamine, chymotrypsin, or elastase induces a conformational modification reminiscent of the one undergone by the transformation of C3 into its active form, C3b.
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Diffuse scattering and partial disorder in complex structures.
Thomas Welberry,Darren Goossens +1 more
TL;DR: This review discusses the state of the field of single-crystal diffuse scattering (SCDS), including detectors, data collection and the modelling techniques, allowing increasingly detailed and quantitative analyses to be undertaken.
Journal ArticleDOI
Molecular replacement: tricks and treats.
TL;DR: To be successful, molecular replacement relies on the quality of the model and of the crystallographic data and some tricks that could be applied to the models or to the crystal to increase the success rate are discussed.
Journal ArticleDOI
Reproducible improvements in order and diffraction limit of crystals of bovine mitochondrial F1-ATPase by controlled dehydration
TL;DR: Dehydrated Orthorhombic crystals of bovine F(1)-ATPase have been subjected to controlled dehydration and diffracted X-rays to 1.8 Angstrom resolution at a synchrotron source, the best diffraction limit yet attained with these crystals, although radiation damage limited the resolution of a complete data set.
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Protein crystallography beamline BL2S1 at the Aichi synchrotron
TL;DR: The protein crystallography beamline BL2S1 has been constructed on the 5 T superbend port of the AichiSR.
References
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Journal ArticleDOI
The Protein Data Bank
Helen M. Berman,John D. Westbrook,Zukang Feng,Gary L. Gilliland,Talapady N. Bhat,Helge Weissig,Ilya N. Shindyalov,Philip E. Bourne +7 more
TL;DR: The goals of the PDB are described, the systems in place for data deposition and access, how to obtain further information and plans for the future development of the resource are described.
Journal ArticleDOI
Crystal structure refinement with SHELXL
TL;DR: New features added to the refinement program SHELXL since 2008 are described and explained.
Journal ArticleDOI
Coot: model-building tools for molecular graphics.
Paul Emsley,Kevin Cowtan +1 more
TL;DR: CCP4mg is a project that aims to provide a general-purpose tool for structural biologists, providing tools for X-ray structure solution, structure comparison and analysis, and publication-quality graphics.
Journal ArticleDOI
PHENIX: a comprehensive Python-based system for macromolecular structure solution
Paul D. Adams,Paul D. Adams,Pavel V. Afonine,Gábor Bunkóczi,Vincent B. Chen,Ian W. Davis,Nathaniel Echols,Jeffrey J. Headd,Li-Wei Hung,Gary J. Kapral,Ralf W. Grosse-Kunstleve,Airlie J. McCoy,Nigel W. Moriarty,Robert D. Oeffner,Randy J. Read,David S. Richardson,Jane S. Richardson,Thomas C. Terwilliger,Peter H. Zwart +18 more
TL;DR: The PHENIX software for macromolecular structure determination is described and its uses and benefits are described.
Journal ArticleDOI
Phaser crystallographic software
Airlie J. McCoy,Ralf W. Grosse-Kunstleve,Paul D. Adams,Martyn Winn,Laurent C. Storoni,Randy J. Read +5 more
TL;DR: A description is given of Phaser-2.1: software for phasing macromolecular crystal structures by molecular replacement and single-wavelength anomalous dispersion phasing.