Citations
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Extensive DNA mimicry by the ArdA anti-restriction protein and its role in the spread of antibiotic resistance
Stephen A. McMahon,Gareth A. Roberts,Kenneth A. Johnson,Laurie P. Cooper,Huanting Liu,John H. White,Lester G. Carter,Bansi Sanghvi,Muse Oke,Malcolm D. Walkinshaw,Garry W. Blakely,James H. Naismith,David T. F. Dryden +12 more
TL;DR: The structure of the ArdA protein from the conjugative transposon Tn916 is solved and it is found that it has a novel extremely elongated curved cylindrical structure with defined helical grooves, explaining how ArdA can bind and inhibit the Type I restriction enzymes.
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Room-temperature serial crystallography using a kinetically optimized microfluidic device for protein crystallization and on-chip X-ray diffraction
Michael Heymann,Achini Opthalage,Jennifer L. Wierman,Sathish Akella,Doletha M. E. Szebenyi,Sol M. Gruner,Seth Fraden +6 more
TL;DR: An emulsion-based serial crystallographic technology has been developed, in which single crystals are grown in nanolitre-sized droplets inside an X-ray semi-transparent microfluidic chip exploiting a negative feedback mechanism.
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Quantitative Rietveld texture analysis of zirconium from single synchrotron diffraction images
TL;DR: In this article, the Rietveld method is applied to obtain quantitative information about the orientation distribution from the analysis of a single synchrotron diffraction image for hexagonal cold-rolled zirconium, investigated in situ in a vacuum furnace with high-energy X-rays.
Journal ArticleDOI
Crystal structures of calcium hemicarboaluminate and carbonated calcium hemicarboaluminate from synchrotron powder diffraction data
TL;DR: The crystal structures of these important AFm phases were successfully solved and refined in the R3c space group of the trigonal crystal system.
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A robust bulk solvent correction and anisotropic scaling procedure in the CCTBX
TL;DR: A robust method for determining bulk-solvent and anisotropic scaling parameters in macromolecular refinement is described and the implementation of a maximum-likelihood target function for determining the same parameters is discussed.
References
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Journal ArticleDOI
The Protein Data Bank
Helen M. Berman,John D. Westbrook,Zukang Feng,Gary L. Gilliland,Talapady N. Bhat,Helge Weissig,Ilya N. Shindyalov,Philip E. Bourne +7 more
TL;DR: The goals of the PDB are described, the systems in place for data deposition and access, how to obtain further information and plans for the future development of the resource are described.
Journal ArticleDOI
Crystal structure refinement with SHELXL
TL;DR: New features added to the refinement program SHELXL since 2008 are described and explained.
Journal ArticleDOI
Coot: model-building tools for molecular graphics.
Paul Emsley,Kevin Cowtan +1 more
TL;DR: CCP4mg is a project that aims to provide a general-purpose tool for structural biologists, providing tools for X-ray structure solution, structure comparison and analysis, and publication-quality graphics.
Journal ArticleDOI
PHENIX: a comprehensive Python-based system for macromolecular structure solution
Paul D. Adams,Paul D. Adams,Pavel V. Afonine,Gábor Bunkóczi,Vincent B. Chen,Ian W. Davis,Nathaniel Echols,Jeffrey J. Headd,Li-Wei Hung,Gary J. Kapral,Ralf W. Grosse-Kunstleve,Airlie J. McCoy,Nigel W. Moriarty,Robert D. Oeffner,Randy J. Read,David S. Richardson,Jane S. Richardson,Thomas C. Terwilliger,Peter H. Zwart +18 more
TL;DR: The PHENIX software for macromolecular structure determination is described and its uses and benefits are described.
Journal ArticleDOI
Phaser crystallographic software
Airlie J. McCoy,Ralf W. Grosse-Kunstleve,Paul D. Adams,Martyn Winn,Laurent C. Storoni,Randy J. Read +5 more
TL;DR: A description is given of Phaser-2.1: software for phasing macromolecular crystal structures by molecular replacement and single-wavelength anomalous dispersion phasing.