Journal ArticleDOI
JAZ repressor proteins are targets of the SCF COI1 complex during jasmonate signalling
Bryan Thines,Leron Katsir,Maeli Melotto,Yajie Niu,Ajin Mandaokar,Guanghui Liu,Kinya Nomura,Sheng Yang He,Gregg A. Howe,John Browse +9 more
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TLDR
The results suggest a model in which jasmonate ligands promote the binding of the SCFCOI1 ubiquitin ligase to and subsequent degradation of the JAZ1 repressor protein, and implicate theSCFCOi1–JAZ1 protein complex as a site of perception of the plant hormone JA–Ile.Abstract:
Jasmonate and related signalling compounds have a crucial role in both host immunity and development in plants, but the molecular details of the signalling mechanism are poorly understood. Here we identify members of the jasmonate ZIM-domain (JAZ) protein family as key regulators of jasmonate signalling. JAZ1 protein acts to repress transcription of jasmonate-responsive genes. Jasmonate treatment causes JAZ1 degradation and this degradation is dependent on activities of the SCF(COI1) ubiquitin ligase and the 26S proteasome. Furthermore, the jasmonoyl-isoleucine (JA-Ile) conjugate, but not other jasmonate-derivatives such as jasmonate, 12-oxo-phytodienoic acid, or methyl-jasmonate, promotes physical interaction between COI1 and JAZ1 proteins in the absence of other plant proteins. Our results suggest a model in which jasmonate ligands promote the binding of the SCF(COI1) ubiquitin ligase to and subsequent degradation of the JAZ1 repressor protein, and implicate the SCF(COI1)-JAZ1 protein complex as a site of perception of the plant hormone JA-Ile.read more
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Journal ArticleDOI
Role of plant hormones in plant defence responses.
TL;DR: Recent advances made in understanding the role of salicylic acid, jasmonates and ethylene in modulating plant defence responses against various diseases and pests are reviewed.
Journal ArticleDOI
Plant Immunity to Insect Herbivores
Gregg A. Howe,Georg Jander +1 more
TL;DR: A detailed understanding of plant immunity to arthropod herbivores will provide new insights into basic mechanisms of chemical communication and plant-animal coevolution and may also facilitate new approaches to crop protection and improvement.
Journal ArticleDOI
The JAZ family of repressors is the missing link in jasmonate signalling
Andrea Chini,Sandra Fonseca,Guillermo Fernández,Bruce Adie,José-Manuel Chico,Oscar Lorenzo,Gloria García-Casado,Irene López-Vidriero,Francisca María Lozano,María Rosa Ponce,José Luis Micol,Roberto Solano +11 more
TL;DR: The identification of JASMONATE-INSENSITIVE 3 (JAI3) and a family of related proteins named JAZ (jasmonate ZIM-domain), in Arabidopsis thaliana and the existence of a regulatory feed-back loop involving MYC2 and JAZ proteins, which provides a mechanistic explanation for the pulsed response to jasmonate and the subsequent desensitization of the cell.
Journal ArticleDOI
Jasmonates: biosynthesis, perception, signal transduction and action in plant stress response, growth and development. An update to the 2007 review in Annals of Botany
Claus Wasternack,Bettina Hause +1 more
TL;DR: Important new components of jasmonate signalling including its receptor were identified, providing deeper insight into the role ofJASMONATE signalling pathways in stress responses and development.
Journal ArticleDOI
Hormone Crosstalk in Plant Disease and Defense: More Than Just JASMONATE-SALICYLATE Antagonism
TL;DR: Recent advances are reported, updating current knowledge on classical defense hormones SA, JA, and ET, and the roles of auxin, abscisic acid (ABA), cytokinins (CKs), and brassinosteroids in molding plant-pathogen interactions are updated.
References
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Journal ArticleDOI
Prostaglandins and Leukotrienes: Advances in Eicosanoid Biology
TL;DR: Important insights into the mechanisms of inflammatory responses, pain, and fever have been gleaned from the current understanding of eicosanoid biology.
Journal ArticleDOI
A gene expression map of Arabidopsis thaliana development
Markus Schmid,Timothy S. Davison,Stefan R. Henz,Utz Johann Pape,Monika Demar,Martin Vingron,Bernhard Schölkopf,Detlef Weigel,Detlef Weigel,Jan U. Lohmann +9 more
TL;DR: Examining the expression patterns of large gene families, it is found that they are often more similar than would be expected by chance, indicating that many gene families have been co-opted for specific developmental processes.
Journal ArticleDOI
The JAZ family of repressors is the missing link in jasmonate signalling
Andrea Chini,Sandra Fonseca,Guillermo Fernández,Bruce Adie,José-Manuel Chico,Oscar Lorenzo,Gloria García-Casado,Irene López-Vidriero,Francisca María Lozano,María Rosa Ponce,José Luis Micol,Roberto Solano +11 more
TL;DR: The identification of JASMONATE-INSENSITIVE 3 (JAI3) and a family of related proteins named JAZ (jasmonate ZIM-domain), in Arabidopsis thaliana and the existence of a regulatory feed-back loop involving MYC2 and JAZ proteins, which provides a mechanistic explanation for the pulsed response to jasmonate and the subsequent desensitization of the cell.
Journal ArticleDOI
COI1: An Arabidopsis Gene Required for Jasmonate-Regulated Defense and Fertility
TL;DR: The coi1 mutation defines an Arabidopsis gene required for response to jasmonates, which regulate defense against insects and pathogens, wound healing, and pollen fertility as mentioned in this paper.
Journal ArticleDOI
Mechanism of auxin perception by the TIR1 ubiquitin ligase
Xu Tan,Luz Irina A. Calderon-Villalobos,Michal Sharon,Changxue Zheng,Carol V. Robinson,Mark Estelle,Ning Zheng +6 more
TL;DR: These structures show that the leucine-rich repeat domain of TIR1 contains an unexpected inositol hexakisphosphate co-factor and recognizes auxin and the Aux/IAA polypeptide substrate through a single surface pocket, establishing the first structural model of a plant hormone receptor.