Junction Adhesion Molecule Is a Receptor for Reovirus
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1,332 citations
Cites background from "Junction Adhesion Molecule Is a Rec..."
...This interaction stimulates nuclear factor- B (NF- B) activation, which results in cellular apoptosis (16)....
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...Interestingly, JAM-A may also mediate heterophilic adhesion to ligands as diverse as the leukocyte L 2-integrin (249) and the attachment protein sigma1 of Reovirus (28)....
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847 citations
Cites background from "Junction Adhesion Molecule Is a Rec..."
...The functional significance of altered JAM-1 expression in membrane rafts may relate to its status as a putative target for pathogens such as reovirus (62)....
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References
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"Junction Adhesion Molecule Is a Rec..." refers methods in this paper
...(Hirt, 1967), amplified in bacteria, and used in three subsequent rounds of FACS enrichment....
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3,728 citations
"Junction Adhesion Molecule Is a Rec..." refers methods in this paper
...Cells were incubated at 378C for various intervals,flammatory cytokines involved in the activation and atand viral titers in lysates were determined by plaque assay.traction of immune effector cells (Pahl, 1999)....
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3,128 citations
"Junction Adhesion Molecule Is a Rec..." refers methods in this paper
...PCR product and Fc-hCAR-pCDNA vided into sub-pools of 5 colonies, and plasmid from sub-pools was 3.1 (Bergelson et al., 1997) were subjected to restriction digest with tested for the capacity to confer enhanced FITC-T3SA2 binding to HindIII and BamHI, resulting in excision of hCAR-encoding…...
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...(Fc-hCAR) was used as a control for nonspecific interactions (Bergelson et al., 1997)....
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2,988 citations
"Junction Adhesion Molecule Is a Rec..." refers background in this paper
...This interval wouldgaged by both antigen and accessory molecules to initiallow for multiple rounds of viral replication prior to cellate effector functions (Grakoui et al., 1999)....
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1,819 citations
"Junction Adhesion Molecule Is a Rec..." refers background in this paper
...Although T3SA1 is Baldwin, 1999; Romashkova and Makarov, 1999)....
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