Knoevenagel condensation in the heterogeneous phase using aluminum phosphate-aluminum oxide as a new catalyst
About: This article is published in Journal of Organic Chemistry.The article was published on 1984-12-01. It has received 200 citations till now. The article focuses on the topics: Knoevenagel condensation & Catalysis.
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337 citations
TL;DR: In this paper, a micelle-templated silica (MTS) was achieved by silanation of the MTS surface by 3-amino and 3-halogeno-propyl alkoxysilane in an apolar solvent.
321 citations
TL;DR: In this article, major advances have been made towards dcsign, realization, and optimization of efficient catalytic systems based on modified aluminosilicate mincrals, and a number of optimizations have been proposed.
Abstract: Major advances have been made towards dcsign, realization, and optimization of efficient catalytic systems based on modified aluminosilicate mincrals.
305 citations
Journal Article•
TL;DR: In this article, the authors proposed a methodology for condensation of aliphatic aldehyde with diethyl malonate, which is not very easy to achieve by conventional reagents, and was not addressed adequately in literature.
Abstract: The basic ionic liquid 1-butyl-3-methylimidazolium hydroxide, [bmIm]OH, efficiently catalyzes Knoevenagel condensation without requirement of any organic solvent. A wide range of aliphatic and aromatic aldehydes and ketones easily undergo condensations with diethyl malonate, malononitrile, ethyl cyanoacetate, malonic acid and ethyl acetoacetate. The reactions proceed at room temperature and are very fast (10-30 min). However, the most significant feature of this methodology is the condensation of aliphatic aldehyde with diethyl malonate, which is not very easy to achieve by conventional reagents, and was not addressed adequately in literature providing a general and convenient procedure.
204 citations
TL;DR: In this article, the condensation of various aromatic and heteroaromatic aldehydes with active methylene compounds like malononitrile, e.g., barbituric acids, Meldrum's acid, dimedone and pyrazolone is described.
190 citations
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Journal Article•
TL;DR: Etude de la condensation de Knoevenagel entre des aldehydes ou des cetones and des dinitriles ou cyanoesters as mentioned in this paper.
Abstract: Etude de la condensation de Knoevenagel entre des aldehydes ou des cetones et des dinitriles ou cyanoesters. Obtention de dinitriles et cyanoesters vinyliques
158 citations