Laboratory Diagnosis of COVID-19: Current Issues and Challenges.
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"Laboratory Diagnosis of COVID-19: C..." refers background in this paper
...Collecting an NP/OP swab specimen may carry a theoretical risk of transmitting SARS-CoV-2, particularly if airborne transmission is demonstrated as the investigation of the COVID-19 outbreak continues (18)....
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...If personal protective equipment (PPE) cannot be utilized due to scarcity of such PPE, other means of collecting upper respiratory tract specimens will be needed (18)....
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...However, low CT values indicating high viral loads may be used as an indication of transmissibility (18, 63)....
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...respiratory tract (4, 18) late in their clinical course....
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...Ideally, sputum sampling or bronchoalveolar lavage should be used for collecting lower respiratory tract specimens as they have yielded the highest viral loads for the diagnosis of COVID-19 (18, 23)....
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9,474 citations
"Laboratory Diagnosis of COVID-19: C..." refers background in this paper
...Coronaviruses have a number of molecular targets within their positive-sense, single-stranded RNA genome that can be used for PCR assays (6, 7, 57, 58)....
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...Among these coronaviruses are a group of SARS-like bat coronaviruses, including both SARS-CoV and SARS-CoV-2, that comprise a unique clade under the subgenus Sarbecovirus (57, 58)....
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...tropism and transmission capability (57, 58)....
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9,231 citations