Large-Scale Reorganization in the Somatosensory Cortex and Thalamus after Sensory Loss in Macaque Monkeys
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Cites background from "Large-Scale Reorganization in the S..."
...The human brain does not exhibit the same topographical mapping as the primate brain [57,58]....
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16 citations
Cites background from "Large-Scale Reorganization in the S..."
...Thus, a few preserved cutaneous inputs from the hand may activate most of the territory of the hand representation in area 3b of monkeys in a matter of weeks, and inputs from the lower face may activate this cortex within 6–8 months (7, 13)....
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...The side for the lesion was selected to minimize damage to surface blood vessels (7, 13)....
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15 citations
15 citations
Cites methods from "Large-Scale Reorganization in the S..."
...Unilateral dorsal column section between spinal cord cervical segments C4–C6 was carried out under aseptic conditions under deep anesthesia (1–3% isoflurane) (Jain et al., 1997, 2008; Qi et al., 2011)....
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...After the completion of the mapping, we were able to identify area 3b, area 1 and S2 and areal borders based on the characteristics of receptive field properties, preferred stimuli and somatotopic organization of the digits (Jain et al., 2008; Kaas et al., 1984)....
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14 citations
References
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"Large-Scale Reorganization in the S..." refers background in this paper
...A small expansion of the face inputs into the hand region of the cortex was seen long after hand or arm amputations (Flor et al., 1995; Florence and Kaas, 1995; Grüsser et al., 2004), or immediately after median and radial nerve injury or block (Silva et al....
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1,327 citations
"Large-Scale Reorganization in the S..." refers background in this paper
...…the cortical maps has been demonstrated in a variety of mammalian species after different kinds of deprivations including digit or limb amputations (Merzenich et al., 1984; Wall and Cusick, 1984; Calford and Tweedale, 1988; Turnbull and Rasmusson, 1991; Florence et al., 1998), nerve transections…...
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...Since then, reorganization of the cortical maps has been demonstrated in a variety of mammalian species after different kinds of deprivations including digit or limb amputations (Merzenich et al., 1984; Wall and Cusick, 1984; Calford and Tweedale, 1988; Turnbull and Rasmusson, 1991; Florence et al., 1998), nerve transections (Wall and Kaas, 1985; Garraghty and Kaas, 1991b), dorsal root transections (Pons et al....
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1,051 citations
"Large-Scale Reorganization in the S..." refers background or methods in this paper
...It is possible that this has not been reported before because the foot region of the cortex was not mapped previously (Pons et al., 1991; Jain et al., 1997)....
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...in macaque monkeys (Pons et al., 1991) and a comparable 5 mm...
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...After an extensive recovery period the boundaries of the face representation shift medially into the hand region by as much as 10 –14 mm in macaque monkeys (Pons et al., 1991) and a comparable 5 mm in smaller owl monkeys (Jain et al., 1997)....
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...Limits of plasticity in area 3b The maximal extent of shift in representational boundaries reported before this study is in the range of 10 –14 mm for macaque monkeys (Pons et al., 1991) and 5 mm for smaller brained owl monkeys (Jain et al....
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...In contrast, after transection of the dorsal roots of the spinal cord from C2 to T4, the deprived hand, arm, and occiput regions of area 3b come to respond to the inputs from the chin (Pons et al., 1991)....
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948 citations