Leukodystrophies: a proposed classification system based on pathological changes and pathogenetic mechanisms.
Citations
274 citations
141 citations
139 citations
101 citations
Cites background from "Leukodystrophies: a proposed classi..."
...Moreover, it has attracted attention in terms of primary microgliopathy.(5,7) Clinical, radiologic, and pathologic characteristics have since been elucidated; however, there are still many questions to be answered....
[...]
95 citations
References
4,075 citations
"Leukodystrophies: a proposed classi..." refers background in this paper
...They are an extremely heterogeneous cell type essential for brain development and maintenance of CNS homeostasis [205]....
[...]
...Astrocytes induce and preserve the integrity of the blood–brain and blood–cerebrospinal fluid barriers, control the extracellular ionic milieu, provide metabolic support to neurons, facilitate perivascular flow of cerebrospinal fluid, ensure proper synaptic transmission and plasticity, and are involved in cerebral blood flow regulation [11, 96, 205]....
[...]
3,238 citations
"Leukodystrophies: a proposed classi..." refers background in this paper
...Being the major immune effectors of the CNS, they also act as surveillance cells and sensors of pathologic events [85]....
[...]
3,108 citations
"Leukodystrophies: a proposed classi..." refers background in this paper
...An essential feature is their dynamic instability that is the possibility to rapidly de- and repolymerize in response to the environment [143]....
[...]
2,330 citations
"Leukodystrophies: a proposed classi..." refers background in this paper
...Cerebral AD arteriopathy with subcortical infarcts and leukoencephalopathy [162]...
[...]
...Cerebral AR arteriopathy with subcortical infarcts and leukoencephalopathy [162]...
[...]
...As a whole, small vessel diseases are a leading cause of functional loss and cognitive decline [162]....
[...]
...Animal studies suggest that restriction of the vessel lumen leads to chronic white matter hypoperfusion resulting in repeated selective oligodendrocyte death and degeneration of myelinated fibers [162, 163, 170]....
[...]
...1 3 term small vessel disease refers to pathological processes with different etiologies affecting small arteries, arterioles, venules and capillaries [162]....
[...]
1,422 citations