Life and death in peripheral T cells
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"Life and death in peripheral T cell..." refers background in this paper
...All caspases are produced by cells as catalytically inactive zymogens and undergo proteolytic processing during activatio...
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5,968 citations
"Life and death in peripheral T cell..." refers background in this paper
...The cell-death receptors, defined by the presence of a DD, include several members of the TNF receptor (TNFR) superfamily: TNFR1, CD95 (also known as FAS or APO-1), TRAIL receptor-1 (TRAILR1), TRAILR2, death receptor 3 (DR3) and DR...
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3,942 citations
"Life and death in peripheral T cell..." refers background in this paper
...In this context, it was shown that T cells from BCL-2-transgenic mice, as well as T cells from mice deficient in both BAX and BAK are not protected from CD95-mediated apoptosi...
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3,829 citations
"Life and death in peripheral T cell..." refers background in this paper
...The NF-κB family of transcription factors regulates the expression of genes crucial for innate and adaptive immune responses, cell growth and apoptosi...
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3,342 citations