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Journal Article

Lifetime body size and prostate cancer risk in a population-based case-control study in sweden

TL;DR: A comprehensive life-course approach revealed no convincing associations between anthropometric measures and prostate cancer risk, however, some leads that deserve further investigation are found, particularly for early-life body size.
Abstract: LIFETIME BODY SIZE AND PROSTATE CANCER RISK IN A POPULATION-BASED CASE-CONTROL STUDY IN SWEDEN
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Journal ArticleDOI
TL;DR: The 2011 Compendium is an update of a system for quantifying the energy cost of adult human PA and is a living document that is moving in the direction of being 100% evidence based.
Abstract: Purpose:The Compendium of Physical Activities was developed to enhance the comparability of results across studies using self-report physical activity (PA) and is used to quantify the energy cost of a wide variety of PA. We provide the second update of the Compendium, called the 2011 Compend

4,712 citations

Journal ArticleDOI
TL;DR: Overall, the data show trends of under‐reporting for weight and BMI and over-reporting for height, although the degree of the trend varies for men and women and the characteristics of the population being examined.
Abstract: Obesity is a rapidly increasing public health problem, with surveillance most often based on self-reported values of height and weight. We conducted a systematic review to determine what empirical evidence exists regarding the agreement between objective (measured) and subjective (reported) measures in assessing height, weight and body mass index (BMI). Five electronic databases were searched to identify observational and experimental studies on adult populations over the age of 18. Searching identified 64 citations that met the eligibility criteria and examined the relationship between self-reported and directly measured height or weight. Overall, the data show trends of under-reporting for weight and BMI and over-reporting for height, although the degree of the trend varies for men and women and the characteristics of the population being examined. Standard deviations were large indicating that there is a great deal of individual variability in reporting of results. Combining the results quantitatively was not possible because of the poor reporting of outcomes of interest. Accurate estimation of these variables is important as data from population studies such as those included in this review are often used to generate regional and national estimates of overweight and obesity and are in turn used by decision makers to allocate resources and set priorities in health.

1,821 citations


"Lifetime body size and prostate can..." refers background in this paper

  • ...Furthermore, self-reported anthropometric data in adulthood may entail overestimation of height and underestimation of weight and BMI [39]....

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01 Jan 2013
TL;DR: The introduction of an effective blood test, prostate specific antigen (PSA), has made it possible to diagnose more and more men in an earlier stage where they can be offered potentially curative treatments, and this is the subject of the EAU guidelines on prostate cancer.
Abstract: The introduction of an effective blood test, prostate specific antigen (PSA), has made it possible to diagnose more and more men in an earlier stage where they can be offered potentially curative treatments. The other side of the coin is that if effective diagnostic procedures are used unselectively in elderly men with a short life expectancy, a problem with over diagnosis and over treatment might occur. Thus the same stage of prostate cancer may need different treatment strategies, pending on the patient’s life expectancy. This, and many other issues regarding the disease, is the subject of the EAU guidelines on prostate cancer. G UI DE LI N ES O N P RO ST AT E CA N CE R 10

968 citations


"Lifetime body size and prostate can..." refers background in this paper

  • ...E. Möller (&) H.-O. Adami C. Lundholm R. Bellocco H. Grönberg K. Bälter Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, P.O. Box 281, SE-171 77 Stockholm, Sweden e-mail: elisabeth.moller@ki.se H.-O. Adami L. A. Mucci Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA L. A. Mucci Channing Division of Network Medicine, Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, MA, USA L. A. Mucci Centre for Public Health Science, University of Iceland, Reykjavik, Iceland R. Bellocco Department of Statistics, University of Milano-Bicocca, Milan, Italy J.-E. Johansson School of Health and Medical Sciences, Örebro University, Örebro, Sweden J.-E. Johansson Department of Urology, Örebro University Hospital, Örebro, Sweden Keywords Prostatic neoplasms Body figure Height Body mass index Weight change Epidemiology...

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  • ...Prostate cancer subtypes were defined by high or low likelihood of tumor progression according to the guidelines of the European Association of Urology [24]....

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Journal ArticleDOI
TL;DR: Prostatic intraepithelial neoplasia and histological cancers are surprisingly common in young male patients of both races, and appears to present several decades earlier than clinically detected carcinoma.

762 citations


"Lifetime body size and prostate can..." refers background in this paper

  • ...The most critical period is potentially before and during puberty, but also early adulthood is likely important as tumorigenic processes in prostatic tissue have been seen in men in their 20s [57]....

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Journal ArticleDOI
TL;DR: Although the proportion of advanced stage cancers was much lower after PSA screening began, risk factors for advanced stage prostate cancers were similar in the pre‐PSA and PSA era.
Abstract: Risk factors for prostate cancer could differ for various sub-groups, such as for "aggressive" and "non-aggressive" cancers or by grade or stage. Determinants of mortality could differ from those for incidence. Using data from the Health Professionals Follow-Up Study, we re-examined 10 factors (cigarette smoking history, physical activity, BMI, family history of prostate cancer, race, height, total energy consumption, and intakes of calcium, tomato sauce and alpha-linolenic acid) using multivariable Cox regression in relation to multiple subcategories for prostate cancer risk. These were factors that we previously found to be predictors of prostate cancer incidence or advanced prostate cancer in this cohort, and that have some support in the literature. In this analysis, only 4 factors had a clear statistically significant association with overall incident prostate cancer: African-American race, positive family history, higher tomato sauce intake (inversely) and alpha-linolenic acid intake. In contrast, for fatal prostate cancer, recent smoking history, taller height, higher BMI, family history, and high intakes of total energy, calcium and alpha-linolenic acid were associated with a statistically significant increased risk. Higher vigorous physical activity level was associated with lower risk. In relation to these risk factors, advanced stage at diagnosis was a good surrogate for fatal prostate cancer, but high-grade (Gleason >/= 7 or Gleason >/= 8) was not. Only for high calcium intake was there a close correspondence for associations among high-grade cancer, advanced and fatal prostate cancer. Tomato sauce (inversely) and alpha-linolenic acid (positively) intakes were strong predictors of advanced cancer among those with low-grade cancers at diagnosis. Although the proportion of advanced stage cancers was much lower after PSA screening began, risk factors for advanced stage prostate cancers were similar in the pre-PSA and PSA era. The complexity of the clinical and pathologic manifestations of prostate cancer must be considered in the design and interpretation of studies.

489 citations


"Lifetime body size and prostate can..." refers background or result in this paper

  • ...Adult height has been positively associated with the disease [5, 7, 13, 20, 21]....

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  • ...The positive associations between adult height and various prostate cancer subtypes are in line with several previous studies [5, 7, 13, 20, 21]....

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  • ...To our knowledge, only two previous studies on BMI in middle to late adulthood adjusted for BMI in early adulthood [11, 20]....

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