Live cell imaging with protein domains capable of recognizing phosphatidylinositol 4,5-bisphosphate; a comparative study
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...This can alter phosphoinositide dynamics, as we and others find (Holz et al., 2000; Raucher et al., 2000; Lei et al., 2001; Várnai et al., 2002; Gamper et al., 2004; Szentpetery et al., 2009)....
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"Live cell imaging with protein doma..." refers background in this paper
...PtdIns(4,5)P2 is also important for endocytosis of PM proteins through its binding to several clathrin adaptors [2]....
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"Live cell imaging with protein doma..." refers background in this paper
...This was finally achieved with the introduction of the PLC1-PH-domain GFP chimera as a molecular probe to detect PtdIns(4,5)P2 in eukaryotic cells [8,9]....
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"Live cell imaging with protein doma..." refers background in this paper
...Moreover, PtdIns(4,5)P2 is required for the proper functioning of many ion channels and transporters [3,4] and also contributes to the regulation of actin polymerization [5] and attachment of the PM to the actin cytoskeleton [6]....
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