Journal ArticleDOI
Long-term immune and cytogenetic effects of high level natural radiation on Ramsar inhabitants in Iran
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TLDR
Research in Ramsar, a northern coastal city of Iran, has some high level natural radiation areas (HLNRAs) as well as over 50 hot springs with low and high radium contents used as spas by the public and vacationers, and shows significant increase of CD69 expression on TCD4+ stimulated cells and total serum IgE and higher incidence of stable and unstable chromosomal aberrations in the HLNRA group compared to the control group with normal background radiation.About:
This article is published in Journal of Environmental Radioactivity.The article was published on 2004-01-01. It has received 60 citations till now. The article focuses on the topics: Population & Environmental exposure.read more
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Biological and cellular responses of humans to high-level natural radiation: A clarion call for a fresh perspective on the linear no-threshold paradigm.
TL;DR: In this article , the authors summarized the data obtained over decades of epidemiological and radiobiological studies on high-level natural radiation areas (HLNRA) populations and showed that no excess cancer risks or untoward pregnancy outcomes were associated with cumulative radiation dose or in-utero exposures.
Journal ArticleDOI
Radon (222Rn) concentrations in the touristic Jumandy cave in the Amazon region of Ecuador.
TL;DR: The average radon concentrations measured in the cavern exceeded the maximum recommended environmental level by a factor of 28, and the effective dose absorbed by the guides exceeded the recommended maximum by a f actor of 10.
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Gene expression profiling of rat livers after continuous whole-body exposure to low-dose rate of gamma rays.
Kim Ngan Tran,Jong-il Choi +1 more
TL;DR: This study showed changes in transcriptome profile of livers from low-dose irradiated rats when compared with that of sham-irradiated ones, and there were a significant number of differentially expressed genes involved in hepatic lipid metabolism.
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Impact of anthropogenic contamination on glacier surface biota.
F Pittino,Jakub Buda,Roberto Ambrosini,Marco Parolini,Arianna Crosta,Krzysztof Zawierucha,Andrea Franzetti +6 more
TL;DR: In this article , the authors provide an overview of the studies that have investigated the effects of pollutants on the supraglacial ecosystem so far, including legacy pollutants, but also compounds still largely used.
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sources and effects of ionizing radiation
TL;DR: This annex is aimed at providing a sound basis for conclusions regarding the number of significant radiation accidents that have occurred, the corresponding levels of radiation exposures and numbers of deaths and injuries, and the general trends for various practices, in the context of the Committee's overall evaluations of the levels and effects of exposure to ionizing radiation.
Journal Article
Chromosomal aberrations in lymphocytes predict human cancer independently of exposure to carcinogens
Stefano Bonassi,Lars Hagmar,Ulf Strömberg,Alicia Huici Montagud,Håkan Tinnerberg,Alessandra Forni,Pirjo Heikkilä,Saskia Wanders,Peter Wilhardt,Inger Lise Hansteen,Lisbeth E. Knudsen,Hannu Norppa +11 more
TL;DR: The risk for high versus low levels of CAs was similar in subjects heavily exposed to carcinogens and in those who had never, to their knowledge, been exposed to any major carcinogenic agent during their lifetime, supporting the idea that chromosome damage itself is involved in the pathway to cancer.
Journal Article
Cancer Risk in Humans Predicted by Increased Levels of Chromosomal Aberrations in Lymphocytes: Nordic Study Group on the Health Risk of Chromosome Damage
Lars Hagmar,Anton Brøgger,Inger-Lise Hansteen,Sverre Heim,Benkt Högstedt,Lisbeth E. Knudsen,Bo Lambert,Kaija Linnainmaa,Felix Mitelman,Ingrid Nordenson,Christina Reuterwall,Sisko Salomaa,Staffan Skerfving,Marja Sorsa +13 more
TL;DR: An increased level of chromosome breakage appears to be a relevant biomarker of future cancer risk in peripheral blood lymphocytes, according to an ongoing Nordic cohort study of cancer incidence.
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Regulation and deregulation of human IgE synthesis
TL;DR: Current understanding of the mechanisms involved in IgE regulation are summarized in this paper, which is of primary importance in defining alterations responsible for the pathological conditions characterized by hyperproduction of IgE.