Journal ArticleDOI
Long-term immune and cytogenetic effects of high level natural radiation on Ramsar inhabitants in Iran
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TLDR
Research in Ramsar, a northern coastal city of Iran, has some high level natural radiation areas (HLNRAs) as well as over 50 hot springs with low and high radium contents used as spas by the public and vacationers, and shows significant increase of CD69 expression on TCD4+ stimulated cells and total serum IgE and higher incidence of stable and unstable chromosomal aberrations in the HLNRA group compared to the control group with normal background radiation.About:
This article is published in Journal of Environmental Radioactivity.The article was published on 2004-01-01. It has received 60 citations till now. The article focuses on the topics: Population & Environmental exposure.read more
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Journal ArticleDOI
Indoor radon monitoring in Northern Iran using passive and active measurements
TL;DR: The dosimetry calculations showed that these four cities could be categorized as average natural radiation zones and the correlation coefficients relating warm and cold season radon variation data were obtained.
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Spontaneous frequency of micronuclei among the newborns from high level natural radiation areas of Kerala in the southwest coast of India.
TL;DR: The baseline frequency of micronuclei in HLNRA newborns is not statistically different from NLN RA newborns suggesting that elevated level of naturally occurring radiation has no significant effect on the induction of micronsuclei frequency among the newborns.
Journal ArticleDOI
Adaptive response of blood lymphocytes of inhabitants residing in high background radiation areas of ramsar- micronuclei, apoptosis and comet assays.
Shahla Mohammadi,Mahnaz Taghavi-Dehaghani,Mohammad R. Gharaati,Reza Masoomi,Mehdi Ghiassi-Nejad +4 more
TL;DR: The results of micronuclei, apoptosis and repair studies suggest that an adaptive response might be induced in people residing in areas with high background radiation.
Journal ArticleDOI
Treatment of Cancer and Inflammation With Low-Dose Ionizing Radiation: Three Case Reports.
Shuji Kojima,Mitsutoshi Tsukimoto,Noriko Shimura,Hironobu Koga,Akishisa Murata,Tsuyoshi Takara +5 more
TL;DR: Three case reports are presented that support the clinical efficacy of low-dose radiation hormesis in patients with cancer and ulcerative colitis and encourage further clinical investigations.
Journal ArticleDOI
Influence of low dose irradiation on differentiation, maturation and T-cell activation of human dendritic cells.
Jutta Jahns,Ulf Anderegg,Anja Saalbach,Britt Rosin,Ina Patties,Annegret Glasow,Manja Kamprad,Markus Scholz,Guido Hildebrandt,Guido Hildebrandt +9 more
TL;DR: It was showed that irradiation of DC-precursors in vitro does not influence surface marker expression or cytokine profile of immature DCs nor of mature DCs after LPS treatment, and there was no difference of single dose irradiation versus fractionated irradiation protocols on the behavior of the matureDCs.
References
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sources and effects of ionizing radiation
TL;DR: This annex is aimed at providing a sound basis for conclusions regarding the number of significant radiation accidents that have occurred, the corresponding levels of radiation exposures and numbers of deaths and injuries, and the general trends for various practices, in the context of the Committee's overall evaluations of the levels and effects of exposure to ionizing radiation.
Journal Article
Chromosomal aberrations in lymphocytes predict human cancer independently of exposure to carcinogens
Stefano Bonassi,Lars Hagmar,Ulf Strömberg,Alicia Huici Montagud,Håkan Tinnerberg,Alessandra Forni,Pirjo Heikkilä,Saskia Wanders,Peter Wilhardt,Inger Lise Hansteen,Lisbeth E. Knudsen,Hannu Norppa +11 more
TL;DR: The risk for high versus low levels of CAs was similar in subjects heavily exposed to carcinogens and in those who had never, to their knowledge, been exposed to any major carcinogenic agent during their lifetime, supporting the idea that chromosome damage itself is involved in the pathway to cancer.
Journal Article
Cancer Risk in Humans Predicted by Increased Levels of Chromosomal Aberrations in Lymphocytes: Nordic Study Group on the Health Risk of Chromosome Damage
Lars Hagmar,Anton Brøgger,Inger-Lise Hansteen,Sverre Heim,Benkt Högstedt,Lisbeth E. Knudsen,Bo Lambert,Kaija Linnainmaa,Felix Mitelman,Ingrid Nordenson,Christina Reuterwall,Sisko Salomaa,Staffan Skerfving,Marja Sorsa +13 more
TL;DR: An increased level of chromosome breakage appears to be a relevant biomarker of future cancer risk in peripheral blood lymphocytes, according to an ongoing Nordic cohort study of cancer incidence.
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Regulation and deregulation of human IgE synthesis
TL;DR: Current understanding of the mechanisms involved in IgE regulation are summarized in this paper, which is of primary importance in defining alterations responsible for the pathological conditions characterized by hyperproduction of IgE.