Lopinavir loaded solid lipid nanoparticles (SLN) for intestinal lymphatic targeting.
Citations
286 citations
Cites background from "Lopinavir loaded solid lipid nanopa..."
...91fold higher for SLN compared to lopinavir suspension [184]....
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...Alex and coworkers developed lopinavir-loaded glyceryl behenate SLN to improve oral bioavailability of lopinavir [184]....
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250 citations
Cites background from "Lopinavir loaded solid lipid nanopa..."
...Numerous studies indicated that the intracellular delivery and bioavailability of drugs encapsulated in SLNs can be significantly enhanced [31, 87]....
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...usually added to the oil phase [30-35] and rarely to the aqueous phase [27, 36]....
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...The group of Souto [31] used SLNs to target intestinal lymphatic vessels in combined anticancer therapy which resulted in significant improvement of bioavailability of antiviral drug....
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References
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"Lopinavir loaded solid lipid nanopa..." refers background in this paper
...…w p b i t a a & 8 w f u a w t f 3 ( a N w s m b e w N r 3 t o c g t 1 t p r b m l a m f u u v p r a t f f fi M g s w 3 u a c p 2 M.R. Aji Alex et al. / European Journal o icroemulsions, self-emulsifying drug delivery systems and polyeric nanoparticles (Araujo et al., 2010; Muchow et al., 2008)....
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