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Journal ArticleDOI

Loss of a circadian adrenal corticosterone rhythm following suprachiasmatic lesions in the rat.

Robert Y. Moore, +1 more
- 13 Jul 1972 - 
- Vol. 42, Iss: 1, pp 201-206
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TLDR
The purpose of the present study was to reinvestigate the role of the central retinal projections in neuroendocrine regulation and find that lesions in the suprachiasmatic region of the hypothalamus abolish the constant estrous response to light in the female rat.
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This article is published in Brain Research.The article was published on 1972-07-13. It has received 2062 citations till now. The article focuses on the topics: Light effects on circadian rhythm & Circadian rhythm.

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Citations
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Journal ArticleDOI

Hypothalamic regulation of sleep and circadian rhythms

TL;DR: These findings explain how various drugs affect sleep and wakefulness, and provide the basis for a wide range of environmental influences to shape wake–sleep cycles into the optimal pattern for survival.
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The mammalian circadian timing system: organization and coordination of central and peripheral clocks.

TL;DR: This work discusses knowledge acquired during the past few years on the complex structure and function of the mammalian circadian timing system and some of the SCN output pathways serve as input pathways for peripheral tissues.
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The two general activation systems of affect: Structural findings, evolutionary considerations, and psychobiological evidence

TL;DR: In this paper, the authors examined two dimensions imbedded in this structure, which they label Negative Activation (NA) and Positive Activation(PA), respectively, and argued that PA and NA represent the subjective components of broader biobehavioral systems.
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Transplanted suprachiasmatic nucleus determines circadian period

TL;DR: The pacemaker role of the suprachiasmatic nucleus in a mammalian circadian system was tested by neural transplantation by using a mutant strain of hamster that shows a short circadian period to restore circadian rhythms to arrhythmic animals whose own nucleus had been ablated.
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Molecular components of the mammalian circadian clock

TL;DR: The general mechanisms of the circadian clockwork are reviewed, recent findings that elucidate tissue-specific expression patterns of the clock genes are described and the importance of circadian regulation in peripheral tissues for an organism's overall well-being is addressed.
References
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Journal ArticleDOI

A retinohypothalamic projection in the rat

TL;DR: The retinohypothalamic tract in the rat appears to arise from the ganglion cells of the retina and to terminate on the smaller dendritic branches of the neurons of the suprachiasmatic nucleus.
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Hormone secretion of the anterior pituitary gland after physical interruption of all nervous pathways to the hypophysiotrophic area.

Béla Halász, +1 more
- 01 Sep 1965 - 
TL;DR: Thyroid weight and structure were similar to those of intact contx*ols and methylthiouracil treatment induced goiter which histologically resembled that of intact treated controls although thyroid weight did not reach the control levels.
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Visual pathway mediating pineal response to environmental light.

TL;DR: Activity of the melatoninforming enzyme, hydroxyindole-O-methyltransferase, in rat pineal is increased when the animal is exposed to continuous darkness, and it is decreased by exposure to continuous light.
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Central control of the pineal gland - Visual pathways.

TL;DR: Denervation of the pineal by superior cervical ganglionectomy abolishes all of the rhythms in the rat pineal gland, and destroying these nerves in the female rat suppresses the vaginal estrus response to continuous environmental illumination.
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