m6A mRNA methylation facilitates resolution of naïve pluripotency toward differentiation
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2,179 citations
Cites background from "m6A mRNA methylation facilitates re..."
...…m6A methyltransferase is crucial for yeast meiosis (Shah and Clancy, 1992; Schwartz et al., 2013), the differentiation of mouse embryonic stem cells (Geula et al., 2015; Wang et al., 2014b), the development of fruit flies (Hongay and Orr-Weaver, 2011) and plants (Zhong et al., 2008),…...
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...…human YTH domain proteins that appear to affect mRNA stability (Harigaya et al., 2006; Hiriart et al., 2012; Kang et al., 2014) and the findings that m6A directs the expression of pluripotency regulators in mouse embryonic stem cells (Batista et al., 2014; Geula et al., 2015; Wang et al., 2014b)....
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1,855 citations
Cites background from "m6A mRNA methylation facilitates re..."
...Mettl3 / mice are not viable, and cells derived from early embryos are unable to resolve their naive pluripotency due to extended transcript lifetime in the complete absence of methylation (Geula et al., 2015)....
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1,373 citations
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1,244 citations
Cites background from "m6A mRNA methylation facilitates re..."
...…m6A modifications have been implicated in development (Ping et al., 2014; Wang et al., 2014b), fertility (Zheng et al., 2013), cell reprogramming (Batista et al., 2014; Chen et al., 2015; Geula et al., 2015), yeast meiosis (Schwartz et al., 2013), and circadian period (Fustin et al., 2013)....
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..., 2013), cell reprogramming (Batista et al., 2014; Chen et al., 2015; Geula et al., 2015), yeast meiosis (Schwartz et al....
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References
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