m6A Regulators Is Differently Expressed and Correlated With Immune Response of Esophageal Cancer
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TLDR
Wang et al. as mentioned in this paper analyzed the gene expression data of 24 major m6A RNA methylation regulators from 775 patients with esophageal cancer from TCGA dataset.Citations
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Targeting the RNA m6A modification for cancer immunotherapy
TL;DR: In this paper , an up-to-date and comprehensive overview of how m6A modifications intrinsically affect immune cells and how alterations in tumor cell modifications extrinsically affect immune cell responses in the tumor microenvironment (TME).
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Targeting the RNA m6A modification for cancer immunotherapy
TL;DR: In this paper , an up-to-date and comprehensive overview of how m6A modifications intrinsically affect immune cells and how alterations in tumor cell modifications extrinsically affect immune cell responses in the tumor microenvironment (TME).
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Functions, mechanisms, and therapeutic implications of METTL14 in human cancer
TL;DR: Zhang et al. as discussed by the authors systematically summarized the latest research progress on METTL14 as a new biomarker for cancer diagnosis and its biological function in human tumors and discuss its potential clinical application.
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N6-methyladenosine modification of CENPK mRNA by ZC3H13 promotes cervical cancer stemness and chemoresistance
TL;DR: The role of N6-methyladenine (m6A) RNA methylation in cervical cancer progression was analyzed using bioinformatics analysis in this paper , which showed that CENPK was directly bound to SOX6 and disrupted the interactions of CENPAR with β-catenin.
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Effects of RNA methylation N6-methyladenosine regulators on malignant progression and prognosis of melanoma.
TL;DR: In this paper, the authors identify genetic markers and assess prognostic performance of N6-methyladenosine (m6A) regulators in melanoma and construct a three-gene risk signature with distinct prognostic value.
References
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Journal ArticleDOI
GEPIA: a web server for cancer and normal gene expression profiling and interactive analyses.
TL;DR: GEPIA (Gene Expression Profiling Interactive Analysis) fills in the gap between cancer genomics big data and the delivery of integrated information to end users, thus helping unleash the value of the current data resources.
Journal ArticleDOI
UALCAN: A Portal for Facilitating Tumor Subgroup Gene Expression and Survival Analyses.
Darshan S. Chandrashekar,Bhuwan Bashel,Sai Akshaya Hodigere Balasubramanya,Chad J. Creighton,Israel Ponce-Rodriguez,Balabhadrapatruni V. S. K. Chakravarthi,Sooryanarayana Varambally +6 more
TL;DR: UALCAN, an easy to use, interactive web-portal to perform to in-depth analyses of TCGA gene expression data, serves as a platform for in silico validation of target genes and for identifying tumor sub-group specific candidate biomarkers.
Journal ArticleDOI
TIMER: A Web Server for Comprehensive Analysis of Tumor-Infiltrating Immune Cells
Taiwen Li,Taiwen Li,Jingyu Fan,Binbin Wang,Nicole Traugh,Qianming Chen,Jun Liu,Bo Li,X. Shirley Liu,X. Shirley Liu +9 more
TL;DR: Tumor Immune Estimation Resource (TIMER) is presented to comprehensively investigate molecular characterization of tumor-immune interactions and provides a user-friendly web interface for dynamic analysis and visualization of these associations, which will be of broad utilities to cancer researchers.
Journal ArticleDOI
Online Survival Analysis Software to Assess the Prognostic Value of Biomarkers Using Transcriptomic Data in Non-Small-Cell Lung Cancer
TL;DR: An integrated database and an online tool capable of uni- and multivariate analysis for in silico validation of new biomarker candidates in non-small cell lung cancer are established.
Journal ArticleDOI
TISIDB: an integrated repository portal for tumor-immune system interactions
Beibei Ru,CN Wong,Yin Tong,Jia Yi Zhong,Sophia Shek Wa Zhong,Wai Chung Wu,Ka Chi Chu,Choi Yiu Wong,Chit Ying Lau,Ian Chen,Nam Wai Chan,Jiangwen Zhang +11 more
TL;DR: A user-friendly web portal TISIDB is designed, which integrated multiple types of data resources in oncoimmunology, and biologists can cross-check a gene of interest about its role in tumor-immune interactions through literature mining and high-throughput data analysis.
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