Mean platelet volume as a predictor of cardiovascular risk: a systematic review and meta-analysis
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...MPV was shown to correlate with platelet activity and is considered a marker of platelet activity [49, 50]; therefore, increased MPV in COVID-19 suggests that these platelets may present as hyperactive....
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...Also, in patients with STEMI infarction, who showed elevated MPV, the application of abciximab decreased mortality [55]....
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...These observations can explain the fact that antiplatelet therapy reduces the risk of complications and in the future also cardiovascular incidents in patients undergoing heart revascularization procedure [55, 63]....
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...Elevated MPV correlates with increased platelet aggregation, enhanced synthesis, and release of thromboxane TXA2 and β-thromboglobulin [55]....
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References
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