Measuring proliferation in breast cancer: practicalities and applications.
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Cites methods or result from "Measuring proliferation in breast c..."
...Various techniques have been developed to quantify proliferation rates, including, mitotic-count estimates, measurement of DNA synthesis, and flow cytometry [1,7-9]....
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...These findings confirm the prognostic relevance of routinely assessed MS in the luminal class, as previously reported in BC [1,7,8]....
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109 citations
References
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"Measuring proliferation in breast c..." refers background in this paper
...High-throughput tissue microarrays can be used to screen for genes with differential expression between cancer cells and normal tissue [89,90] and gene expression signatures have been developed that can predict survival in breast cancer [91,92]....
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5,902 citations
5,575 citations
Additional excerpts
...Mitotic count estimates are widely used as a simple measure of cellular proliferation and are often incorporated into tumour grading systems [3]....
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2,722 citations
"Measuring proliferation in breast c..." refers background in this paper
...In 1982 Gratzner [16] described the use of monoclonal...
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...In 1982 Gratzner [16] described the use of monoclonal antibodies specific for 5-bromodeoxyuridine (BrdU) in the detection of DNA replication....
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2,226 citations