Measuring the thickness of the human cerebral cortex from magnetic resonance images
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9,940 citations
Cites background or methods from "Measuring the thickness of the huma..."
...…representations) available on images of the cortex that are Finflated_ (Dale and Sereno, 1993; Dale et al., 1999; Fischl et al., 1999a,b, 2001; Fischl and Dale, 2000); anatomic curvature is visually represented well on inflated images as they provide a view of the brain in which the entire…...
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...First, we have developed the definitions of the regions of interest using curvature based information (i.e., sulcal representations) available on images of the cortex that are Finflated_ (Dale and Sereno, 1993; Dale et al., 1999; Fischl et al., 1999a,b, 2001; Fischl and Dale, 2000); anatomic curvature is visually represented well on inflated images as they provide a view of the brain in which the entire cortical surface is exposed, including the tissue deep in the sulci....
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..., sulcal representations) available on images of the cortex that are Finflated_ (Dale and Sereno, 1993; Dale et al., 1999; Fischl et al., 1999a,b, 2001; Fischl and Dale, 2000); anatomic curvature is visually represented well on inflated images as they provide a view of the brain in which the entire cortical surface is exposed, including the tissue deep in the sulci....
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...The cortical white matter surfaces generated by the steps above were automatically corrected for topological defects (Fischl et al., 2001; Ségonne et al., 2005), and thereafter utilized in a deformation procedure that locates the pial (gray matter) surface of the brain (Fischl and Dale, 2000)....
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...The yellow asterisks on the inflated surface (right) indicate the cortex around the perimeter of the central sulcus that has been Finflated_ and is now visible....
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3,880 citations
Cites methods from "Measuring the thickness of the huma..."
...Cortical models were reconstructed for each of the subjects using previously presented techniques, including non-rigid surface-based alignment to a previously constructed spherical atlas (Dale and Sereno, 1993; Dale, Fischl et al., 1999; Fischl, Sereno et al., 1999; Fischl, Sereno et al., 1999; Fischl and Dale, 2000; Fischl, Liu et al., 2001)....
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...For the CMA parcellation we first sample the volumetric labeling onto the reconstructed cortical surface of each subject (Dale, Fischl et al., 1999; Fischl, Sereno et al., 1999; Fischl and Dale, 2000; Fischl, Liu et al., 2001), the subsequent procedures for the two parcellations are identical....
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...14 manual parcellations were then sampled onto the cortical models at the midpoint of the cortical ribbon using the thickness estimates described in (Fischl and Dale, 2000)....
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...For the CMA parcellation we first sample the volumetric labeling onto the reconstructed cortical surface of each subject (Dale et al., 1999; Fischl et al., 1999a, 2001; Fischl and Dale, 2000), the subsequent procedures for the two parcellations are identical....
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...The manual parcellations were then sampled onto the cortical models at the midpoint of the cortical ribbon using the thickness estimates described in Fischl and Dale (2000)....
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3,491 citations
Cites methods from "Measuring the thickness of the huma..."
..., 2005), SyN, and Freesurfer (Fischl and Dale, 2000) on whole head data and found that both brain extraction and registration via an “optimal” (groupgenerated) template improve performance....
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...0 (Ardekani et al., 2005), SyN, and Freesurfer (Fischl and Dale, 2000) on whole head data and found that both brain extraction and registration via an “optimal” (groupgenerated) template improve performance....
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2,679 citations
Cites background from "Measuring the thickness of the huma..."
...We believe that cortex is the best target for two reasons: (1) it is highly folded, allowing dense sampling of 3D space, and, (2) it is very thin (2.5 mm on average; Fischl and Dale, 2000), implying that small alignment errors will generate large changes in the cost function....
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...Cortex has a typical thickness of between 1 and 5 mm (Fischl and Dale, 2000)....
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1,949 citations
Cites background from "Measuring the thickness of the huma..."
..., 2007), and surface deformation following intensity gradients to optimally place the gray/white and gray/CSF borders at the location where the greatest shift in intensity defines the transition to the other tissue class (Fischl and Dale, 2000)....
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...…correction (Fischl et al., 2001; Ségonne et al., 2007), and surface deformation following intensity gradients to optimally place the gray/white and gray/CSF borders at the location where the greatest shift in intensity defines the transition to the other tissue class (Fischl and Dale, 2000)....
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References
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"Measuring the thickness of the huma..." refers methods in this paper
...In conjunction with automated surface reconstruction [21-24] and high-resolution surface averaging techniques [25], the measurement of cortical thickness with sub-millimeter accuracy facilitates the use of powerful statistical methods in the investigation of neurodegeneration and recovery....
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...These include methods for constructing [22, 24] and transforming [23] models of the human cerebral cortex, as well as a means for using the pattern of cortical folding derived from these models to drive a high-resolution inter-subject alignment procedure [25]....
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...The surface of the connected white matter voxels is then refined to obtain sub-voxel accuracy in the representation of the gray/white boundary, and subsequently deformed outward to find the pial surface, as described in [22]....
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9,491 citations