Journal ArticleDOI
Mechanism of Lysozyme Action
David M. Chipman,Nathan Sharon +1 more
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This article is published in Science.The article was published on 1969-08-01. It has received 574 citations till now.read more
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Theoretical studies of enzymic reactions: Dielectric, electrostatic and steric stabilization of the carbonium ion in the reaction of lysozyme
TL;DR: Electrostatic stabilization is an important factor in increasing the rate of the reaction step that leads to the formation of the carbonium ion intermediate, found in the cleavage of a glycosidic bond by lysozyme.
Book ChapterDOI
Hydration of Proteins and Polypeptides
Irwin D. Kuntz,W. Kauzmann +1 more
TL;DR: The chapter presents several proposals for predicting protein hydration based on the amino acid composition of the protein; however, the two main questions concerned include—whether ionic groups are more hydrated than other polar groups, and whether the amide and peptide functions are hydrated or not.
Journal ArticleDOI
Nutritional and physiologic significance of human milk proteins
TL;DR: Human milk contains a wide variety of proteins that contribute to its unique qualities, such as immunoglobulins, cytokines and lactoferrin, and peptides have immunomodulatory activities.
Book ChapterDOI
2 – Isolation, Physicochemical Characterization, and Carbohydrate-Binding Specificity of Lectins
Journal ArticleDOI
Aromatic contributions to circular dichroism spectra of proteins.
TL;DR: Aromatic Contributions To Circular Dichroism Spectra Of Protein this paper were discussed in detail in the CRC Critical Reviews in Biochemistry: Vol. 2, No. 1, pp. 113-175.
References
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Journal ArticleDOI
On the size of the active site in proteases. I. Papain.
Israel Schechter,Arieh Berger +1 more
Journal ArticleDOI
Application of a Theory of Enzyme Specificity to Protein Synthesis
TL;DR: The suggestion of Lipmann' that the energy required to drive this reaction to the right came from adenosine triphosphate has been supported by the extensive work and an analysis of why this linking of amino acids presents such formidable difficulties is revealing.
Journal ArticleDOI
Structure of hen egg-white lysozyme. A three-dimensional Fourier synthesis at 2 Angstrom resolution.
C. C. F. Blake,D. F. Koenig,D. F. Koenig,G. A. Mair,A. C. T. North,D. C. Phillips,V. R. Sarma +6 more
TL;DR: Structure of Hen Egg-White Lysozyme: A Three-dimensional Fourier Synthesis at 2 A Resolution as mentioned in this paper, 3D Fourier synthesis at 2 a resolution.
Journal ArticleDOI
Serum and urinary lysozyme (muramidase) in monocytic and monomyelocytic leukemia
TL;DR: Present evidence indicates that ly sozyme is the principal, if not the sole, product of the proliferating monocytes in monocytic and monomyelocytic leukemia, and quantitation of serum and urine lysozyme should be a useful diagnostic procedure for these leukemias.
Journal ArticleDOI
On a Remarkable Bacteriolytic Element Found in Tissues and Secretions
TL;DR: A substance present in the tissues and secretions of the body, which is capable of rapidly dissolving certain bacteria, is called a “Lysozyme,” and is alluded to as the Micrococcus lysodeikticus.