Medication adherence in schizophrenia: factors influencing adherence and consequences of nonadherence, a systematic literature review
Citations
140 citations
Cites background from "Medication adherence in schizophren..."
...Non-adherence issues need to be looked at from many angles and taking a multifaceted approaches with patients and healthcare providers to address identified challenges [81]....
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...The heterogeneity of factors related to non-adherence calls for individually tailored approaches to promote adherence [80, 81]....
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121 citations
Cites background from "Medication adherence in schizophren..."
...The partial- and total nonadherence to oral antipsychotic therapy that is common among patients with schizophrenia has significant impacts on treatment outcomes and healthcare resources (Higashi et al., 2013; Fleischhacker et al., 2014)....
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116 citations
Cites result from "Medication adherence in schizophren..."
...These findings were similar to that seen in recent systematic reviews conducted in schizophrenia, where most of the studies included found an increase in overall direct medical and healthcare costs in patients who were non-adherent (Dilla et al., 2013; Higashi et al., 2013)....
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...structive pulmonary disease (COPD) (Bitton et al., 2013; Dilla et al., 2013; Higashi et al., 2013; van Boven et al., 2014)....
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108 citations
101 citations
References
25,711 citations
8,021 citations
"Medication adherence in schizophren..." refers background or methods in this paper
...nonadherence drivers or consequences) based on abstract screening [Liberati et al. 2009]....
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...Thus a very broad search strategy was adopted in order to avoid missing potentially relevant information, with the identification of relevant studies per outcome (i.e. nonadherence drivers or consequences) based on abstract screening [Liberati et al. 2009]....
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5,437 citations
"Medication adherence in schizophren..." refers methods in this paper
...Data from the Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) study showed that 74% of patients had discontinued medication within 18 months due to insufficient efficacy, intolerable side effects or for other reasons [Lieberman, 2005]....
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619 citations
"Medication adherence in schizophren..." refers background or methods or result in this paper
...In addition, there was one retrospective database study [Valenstein et al. 2004] and one review/survey of experts [Velligan et al. 2009]....
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...The expert survey [Velligan et al. 2009] rated distress associated with persistent side effects (especially weight gain in women and excessive sedation) to be important contributors to adherence problems....
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...Physician perception on important factors of nonadherence In the expert survey [Velligan et al. 2009] on potential contributors to adherence problems in schizophrenia, experts were asked to rate factors as very important, somewhat important and not important for medication adherence....
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...…and Weiden, 2009; Laan et al. 2010; Law et al. 2008; Leucht and Heres, 2006; Llorca, 2008; Marcus and Olfson, 2008; Morken et al. 2008; Rittmannsberger et al. 2004; Rzewuska, 2002; Svarstad et al. 2001; Svestka and Bitter, 2007; Valenstein et al. 2002; Velligan et al. 2009; Weiden et al. 2004a]....
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...Furthermore, a review [Velligan et al. 2009] reported that the ‘positive relationship with clinical staff ’ was a significant predictor of good adherence....
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615 citations
"Medication adherence in schizophren..." refers background or methods or result in this paper
...…and Weiden, 2009; Laan et al. 2010; Law et al. 2008; Leucht and Heres, 2006; Llorca, 2008; Marcus and Olfson, 2008; Morken et al. 2008; Rittmannsberger et al. 2004; Rzewuska, 2002; Svarstad et al. 2001; Svestka and Bitter, 2007; Valenstein et al. 2002; Velligan et al. 2009; Weiden et al. 2004a]....
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...…Karve et al. 2009; Kozma and Weiden, 2009; Laan et al. 2010; Law et al. 2008; Marcus and Olfson, 2008; Svarstad et al. 2001; Valenstein et al. 2002; Weiden et al. 2004a] and five reviews [Byerly et al. 2007; Leucht and Heres, 2006; Llorca, 2008; Svestka and Bitter, 2007; Velligan et al. 2009]....
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...…studies [Ahn et al. 2008; Ascher-Svanum et al. 2006; Eaddy et al. 2005; Gilmer et al. 2004; Karve et al. 2009; Knapp et al. 2004; Kozma and Weiden, 2009; Law et al. 2008; Marcus and Olfson, 2008; Svarstad et al. 2001; Valenstein et al. 2002; Weiden et al. 2004a] included more than 500 subjects....
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...…et al. 2003; McCann et al. 2009; Novick et al. 2010; Olfson et al. 2006; Rettenbacher et al. 2004; Valenstein et al. 2004; Velligan et al. 2009; Weiden et al. 2004b] assessed drivers of nonadherence in schizophrenia; seven were prospective longitudinal studies [Acosta et al. 2009;…...
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...…Hudson et al. 2004; Janssen et al. 2006; Linden et al. 2001; Loffler et al. 2003; Novick et al. 2010; Olfson et al. 2006; Valenstein et al. 2004; Weiden et al. 2004b] included more than 100 subjects (i.e. patients or psychiatrists), and five of these studies [AscherSvanum 2006; Janssen et al.…...
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