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Journal ArticleDOI

Meta-Analysis in Clinical Trials*

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TLDR
This paper examines eight published reviews each reporting results from several related trials in order to evaluate the efficacy of a certain treatment for a specified medical condition and suggests a simple noniterative procedure for characterizing the distribution of treatment effects in a series of studies.
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This article is published in Controlled Clinical Trials.The article was published on 1986-09-01. It has received 33234 citations till now. The article focuses on the topics: Study heterogeneity & Meta-analysis.

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Citations
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Systematic review and meta-analysis

TL;DR: In this review the usual methods applied in systematic reviews and meta-analyses are outlined, and the most common procedures for combining studies with binary outcomes are described, illustrating how they can be done using Stata commands.
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Quantifying heterogeneity in a meta‐analysis

TL;DR: It is concluded that H and I2, which can usually be calculated for published meta-analyses, are particularly useful summaries of the impact of heterogeneity, and one or both should be presented in publishedMeta-an analyses in preference to the test for heterogeneity.
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The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate healthcare interventions: explanation and elaboration

TL;DR: The meaning and rationale for each checklist item is explained, and an example of good reporting is included and, where possible, references to relevant empirical studies and methodological literature are included.
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Conducting Meta-Analyses in R with the metafor Package

TL;DR: The metafor package provides functions for conducting meta-analyses in R and includes functions for fitting the meta-analytic fixed- and random-effects models and allows for the inclusion of moderators variables (study-level covariates) in these models.
References
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Book

Statistical Methods for Meta-Analysis

TL;DR: In this article, the authors present a model for estimating the effect size from a series of experiments using a fixed effect model and a general linear model, and combine these two models to estimate the effect magnitude.
Book

Statistical Methods in Cancer Research

N. E. Breslow
TL;DR: Statistical methods in cancer research as mentioned in this paper, Statistical Methods in Cancer Research, Statistical methods in Cancer research, Statistical methods for cancer research, کتابخانه مرکزی دانشگاه علوم پزش
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Maximum Likelihood Approaches to Variance Component Estimation and to Related Problems

TL;DR: In this paper, the authors proposed a restricted maximum likelihood (reml) approach which takes into account the loss in degrees of freedom resulting from estimating fixed effects, and developed a satisfactory asymptotic theory for estimators of variance components.
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Evidence favoring the use of anticoagulants in the hospital phase of acute myocardial infarction.

TL;DR: The sample sizes in these "negative" papers were too small to protect against missing a 21% reduction in true case fatality rate due to anticoagulation, so all patients who present no specific contraindication should receive antICOagulants during hospitalization for infarction.
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