Metabolic reprogramming of cancer-associated fibroblasts by IDH3α downregulation.
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120 citations
"Metabolic reprogramming of cancer-a..." refers background in this paper
..., 1999), progression (Dimanche-Boitrel et al., 1994; Orimo et al., 2005), and metastasis (Grum-Schwensen et al....
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...Through specific communications with cancer cells, CAFs directly promote tumor initiation (Bhowmick et al., 2004; Olumi et al., 1999), progression (Dimanche-Boitrel et al., 1994; Orimo et al., 2005), and metastasis (Grum-Schwensen et al., 2005; Olaso et al., 1997)....
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116 citations
"Metabolic reprogramming of cancer-a..." refers background in this paper
...In addition, caveolin (CAV1), a potential onco-protein (Sotgia et al., 2009, 2012), was downregulated in these CAFs....
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105 citations
"Metabolic reprogramming of cancer-a..." refers background in this paper
...PHD2 was found to directly regulate HIF-1a hydroxylation (Lee et al., 2008; Minervini et al., 2013; Tennant et al., 2009)....
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55 citations
"Metabolic reprogramming of cancer-a..." refers background in this paper
...PHD2 was found to directly regulate HIF-1a hydroxylation (Lee et al., 2008; Minervini et al., 2013; Tennant et al., 2009)....
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45 citations
"Metabolic reprogramming of cancer-a..." refers methods in this paper
...For the ODD luciferase assay, the ODD domain of HIF-1a (GenBank accession number U59496) was fused to the 50 end of the firefly luciferase reporter gene (Dewhirst et al., 2007)....
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